Summary of vector injections in mice
| MOIs per mouse* . | Total no. transducing units per mouse . | Total viral particle no. per kg body weight . | Total no. transducing units per kg body weight . |
|---|---|---|---|
| 20 | 2 × 109 | 1.8 × 1011 | 9.1 × 1010 |
| 10 | 1 × 109 | 9.1 × 1010 | 4.5 × 1010 |
| 5 | 5 × 108 | 4.5 × 1010 | 2.3 × 1010 |
| 1 | 1 × 108 | 9.1 × 109 | 4.5 × 109 |
| MOIs per mouse* . | Total no. transducing units per mouse . | Total viral particle no. per kg body weight . | Total no. transducing units per kg body weight . |
|---|---|---|---|
| 20 | 2 × 109 | 1.8 × 1011 | 9.1 × 1010 |
| 10 | 1 × 109 | 9.1 × 1010 | 4.5 × 1010 |
| 5 | 5 × 108 | 4.5 × 1010 | 2.3 × 1010 |
| 1 | 1 × 108 | 9.1 × 109 | 4.5 × 109 |
For comparison, the amount of transducing units per mouse, total amount of transducing units, and viral particles per kilogram body weight are shown.
MOIs indicates multiplicities of infection.
For all experiments, mice at the age of 8 weeks were used. It is assumed that a mouse liver at the age of 8 weeks contained approximately 1 × 108 hepatocytes.