Table 4. Effect of HLA allele mismatch... | American Society of Hematology

Table 4.

Effect of HLA allele mismatch on chronic graft-versus-host disease

HLA mismatch locus	No. of cases	Incidence (%) of chronic GVHD
HLA mismatch locus	No. of cases	LD + EX	P^4-150	EX	P^4-150
Match	310	44.8	—	29.9	—
A/B	67	59.6	.004	40.2	.015
C	86	50.5	.178	37.6	.146
DR/DQ	60	40.5	.960	31.5	.546
A/B + C	74	51.0	.163	33.2	.429
A/B + DR/DQ	26	55.2	.135	39.7	.188
C + DR/DQ	39	52.5	.084	37.8	.103
A/B + C + DR/DQ	32	76.8	.010	53.3	.021

HLA mismatch locus	No. of cases	Incidence (%) of chronic GVHD
HLA mismatch locus	No. of cases	LD + EX	P^4-150	EX	P^4-150
Match	310	44.8	—	29.9	—
A/B	67	59.6	.004	40.2	.015
C	86	50.5	.178	37.6	.146
DR/DQ	60	40.5	.960	31.5	.546
A/B + C	74	51.0	.163	33.2	.429
A/B + DR/DQ	26	55.2	.135	39.7	.188
C + DR/DQ	39	52.5	.084	37.8	.103
A/B + C + DR/DQ	32	76.8	.010	53.3	.021

GVHD indicates graft-versus-host disease; LD, limited type; EX, extensive type.

P value compared with matched cases by univariate analyses.