Testing for a trend in risk of CLL associated with one or more putative high-risk GST genotypes
| No. of “high-risk” genotypes . | GST status . | Cases (n = 138) . | Controls (n = 263) . | Odds ratio . | 95% confidence interval . | ||
|---|---|---|---|---|---|---|---|
| GSTM1 . | GSTT1 . | GSTP1 . | |||||
| 0 | present | present | Ile-Ile | 17 | 58 | 1 | |
| 1 | present | null | Ile-Ile | 58 | 100 | 2.0 | 1.1-3.7 |
| null | present | Ile-Ile | |||||
| present | present | Ile-Val, Val-Val | |||||
| 2 | null | null | Ile-Ile | 50 | 89 | 1.9 | 1.0-3.6 |
| null | present | Ile-Val, Val-Val | |||||
| present | null | Ile-Val, Val-Val | |||||
| 3 | null | null | Ile-Val, Val-Val | 13 | 16 | 2.8 | 1.1-6.9 |
| Ptrend= .04 | |||||||
| No. of “high-risk” genotypes . | GST status . | Cases (n = 138) . | Controls (n = 263) . | Odds ratio . | 95% confidence interval . | ||
|---|---|---|---|---|---|---|---|
| GSTM1 . | GSTT1 . | GSTP1 . | |||||
| 0 | present | present | Ile-Ile | 17 | 58 | 1 | |
| 1 | present | null | Ile-Ile | 58 | 100 | 2.0 | 1.1-3.7 |
| null | present | Ile-Ile | |||||
| present | present | Ile-Val, Val-Val | |||||
| 2 | null | null | Ile-Ile | 50 | 89 | 1.9 | 1.0-3.6 |
| null | present | Ile-Val, Val-Val | |||||
| present | null | Ile-Val, Val-Val | |||||
| 3 | null | null | Ile-Val, Val-Val | 13 | 16 | 2.8 | 1.1-6.9 |
| Ptrend= .04 | |||||||