Table 1.

Main laboratory features of the patient's plasma

PatientNormal values
PTT 13.3 s 13.4 s 
aPTT 31.2 s 30-40 s 
Antithrombin activity 116% 80%-120% 
Protein C antigen (ELISA) 100% 80%-120% 
Protein C activity (amidolytic) 98% 70%-130% 
Protein C activity (clotting) 40% 80%-120% 
Protein C activity (clotting) in PC-deficient plasma reconstituted with 4 μg/mL PC isolated from patient's plasma 100% 80%-120%  
Total protein S antigen 90% 70%-130%  
Free protein S antigen 88% 70%-130%  
Protein S clotting activity 35% 65%-135%  
Protein S activity (clotting) in PS- deficient plasma reconstituted with 10 μg/mL PS isolated from patient's plasma 90% 65%-135%  
Factor V antigen 100% 80%-120%  
Factor V activity 102% 80%-120% 
APC-SR 1.14 > 2.00  
Factor VLeiden mutation Homozygous wild-type Homozygous wild-type 
PatientNormal values
PTT 13.3 s 13.4 s 
aPTT 31.2 s 30-40 s 
Antithrombin activity 116% 80%-120% 
Protein C antigen (ELISA) 100% 80%-120% 
Protein C activity (amidolytic) 98% 70%-130% 
Protein C activity (clotting) 40% 80%-120% 
Protein C activity (clotting) in PC-deficient plasma reconstituted with 4 μg/mL PC isolated from patient's plasma 100% 80%-120%  
Total protein S antigen 90% 70%-130%  
Free protein S antigen 88% 70%-130%  
Protein S clotting activity 35% 65%-135%  
Protein S activity (clotting) in PS- deficient plasma reconstituted with 10 μg/mL PS isolated from patient's plasma 90% 65%-135%  
Factor V antigen 100% 80%-120%  
Factor V activity 102% 80%-120% 
APC-SR 1.14 > 2.00  
Factor VLeiden mutation Homozygous wild-type Homozygous wild-type 
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