Table 1. Clinical features and FLT3... | American Society of Hematology

Table 1.

Clinical features and FLT3 mutations in AML and RAEB-t patients at diagnosis

	ITD neg + TKD wt (median, range)	ITD pos + TKD wt (median, range)	ITD neg + TKD mut (median, range)	ITD pos + TKD mut (median, range)
Absolute leukocyte counts (× 10⁹/L)	10.9 (0.32-380.0)	52.0^* (0.4-465.9)	40.1^* (0.9-320.0)	50.7^† (3.6-183.0)
N =	704	177	54	16
Bone marrow blasts (%)	57.0 (3.5-99.0)^1-153	73.5^* (20-99)^1-153	68.0^† (19.5-96.5)^1-153	71.3 (42.0-83.0)^1-153
N =	687	164	51	14
CD34⁺ cells (%)	30 (0-98)	20^‡ (0-96)	22 (0-91)	10 (3-73)
N =	636	167	49	15

	ITD neg + TKD wt (median, range)	ITD pos + TKD wt (median, range)	ITD neg + TKD mut (median, range)	ITD pos + TKD mut (median, range)
Absolute leukocyte counts (× 10⁹/L)	10.9 (0.32-380.0)	52.0^* (0.4-465.9)	40.1^* (0.9-320.0)	50.7^† (3.6-183.0)
N =	704	177	54	16
Bone marrow blasts (%)	57.0 (3.5-99.0)^1-153	73.5^* (20-99)^1-153	68.0^† (19.5-96.5)^1-153	71.3 (42.0-83.0)^1-153
N =	687	164	51	14
CD34⁺ cells (%)	30 (0-98)	20^‡ (0-96)	22 (0-91)	10 (3-73)
N =	636	167	49	15

P < .001;

P < .01;

P < .05.

Some patients had FAB M6.