Types of FLT3 mutations found in codons 835 and 836 of the second TKD
| Mutation . | N . | Amino acid change . | Remarks . |
|---|---|---|---|
| 835 GAT → TAT | 34 | Asp → Tyr | — |
| 835 GAT → CAT | 18 | Asp → His | — |
| 835 GAT → GTT | 5 | Asp → Val | — |
| 835 GAT → GAG | 8 | Asp → Glu | — |
| 835 GAT → GAG | 2 | Asp → Asn | Combined with other mutations |
| 835 GAT → GGT | 4 | Asp → Gly | — |
| 835 GAT → multiple | 1 | Asp → ins. Leucin-Lysin | Combined with 836 isoleucin-serin |
| — | |||
| 836 ATC → Del | 13 | Ile → Del | — |
| 836 ATC → ATGCGC | 1 | Ile → MetArg | Insertion of arginin |
| 836 ATC → ACC | 1 | Ile → Thr | — |
| Mutation . | N . | Amino acid change . | Remarks . |
|---|---|---|---|
| 835 GAT → TAT | 34 | Asp → Tyr | — |
| 835 GAT → CAT | 18 | Asp → His | — |
| 835 GAT → GTT | 5 | Asp → Val | — |
| 835 GAT → GAG | 8 | Asp → Glu | — |
| 835 GAT → GAG | 2 | Asp → Asn | Combined with other mutations |
| 835 GAT → GGT | 4 | Asp → Gly | — |
| 835 GAT → multiple | 1 | Asp → ins. Leucin-Lysin | Combined with 836 isoleucin-serin |
| — | |||
| 836 ATC → Del | 13 | Ile → Del | — |
| 836 ATC → ATGCGC | 1 | Ile → MetArg | Insertion of arginin |
| 836 ATC → ACC | 1 | Ile → Thr | — |