Induction outcome as a function of treatment presence or absence of DiOC2(3) efflux modulated by PSC-833 in vitro in patients with pretreatment samples studied for MDR
. | Efflux positive (n = 43) . | Efflux negative (n = 23) . | Total (n = 66) . | P . |
---|---|---|---|---|
ADE | ||||
CR | 9 (41%) | 10 (91%) | 19 (58%) | .03 |
NR | 9 (41%) | 1 (9%) | 10 (30%) | |
Death | 4 (18%) | 0 (0%) | 4 (12%) | |
Total | 22 | 11 | 33 | |
ADEP | ||||
CR | 10 (48%) | 6 (50%) | 16 (48%) | 1.0 |
NR | 4 (19%) | 2 (17%) | 6 (18%) | |
Death | 7 (33%) | 4 (33%) | 11 (33%) | |
Total | 21 | 12 | 33 |
. | Efflux positive (n = 43) . | Efflux negative (n = 23) . | Total (n = 66) . | P . |
---|---|---|---|---|
ADE | ||||
CR | 9 (41%) | 10 (91%) | 19 (58%) | .03 |
NR | 9 (41%) | 1 (9%) | 10 (30%) | |
Death | 4 (18%) | 0 (0%) | 4 (12%) | |
Total | 22 | 11 | 33 | |
ADEP | ||||
CR | 10 (48%) | 6 (50%) | 16 (48%) | 1.0 |
NR | 4 (19%) | 2 (17%) | 6 (18%) | |
Death | 7 (33%) | 4 (33%) | 11 (33%) | |
Total | 21 | 12 | 33 |
NR indicates alive, with no response.