Initial rates of 50 nM WT and Arg67His prothrombin activation by either 10 nM FXa alone or a combination of 10 nM FXa plus 5 nM FVa
| Activating agent . | WT-FII vobs (pM/min) . | Arg67His-FII vobs (pM/min) . |
|---|---|---|
| FXa | 6.5 ± 0.94-150 | 5.7 ± 0.1 |
| FXa + FVa | 500 ± 90 | 100 ± 15 |
| Activating agent . | WT-FII vobs (pM/min) . | Arg67His-FII vobs (pM/min) . |
|---|---|---|
| FXa | 6.5 ± 0.94-150 | 5.7 ± 0.1 |
| FXa + FVa | 500 ± 90 | 100 ± 15 |
Results are based on the experimental conditions reported in text.
The values of mean ± SD from 2 different measurements are reported.