Plasma HK and PK values in the patient and his family
. | HK activity (U/mL)* . | PK activity (U/mL)* . | PK antigen (μg/mL)† . |
|---|---|---|---|
| Proband | <0.01 | 0.27 | 9.8 |
| Father | 0.38 | 0.24 | 14.3 |
| Mother | 0.59 | 0.24 | 18.6 |
| Sister | 0.65 | 0.21 | 24.4 |
. | HK activity (U/mL)* . | PK activity (U/mL)* . | PK antigen (μg/mL)† . |
|---|---|---|---|
| Proband | <0.01 | 0.27 | 9.8 |
| Father | 0.38 | 0.24 | 14.3 |
| Mother | 0.59 | 0.24 | 18.6 |
| Sister | 0.65 | 0.21 | 24.4 |
Both HK procoagulant activity and PK chromogenic activity of the patient samples were compared against a pool of normal human plasma which by convention has one U/mL HK and PK activity.
PK antigen was determined by radial immunodiffusion assay with comparison with a standardized pool of normal human plasma. The PK antigen concentration in this plasma is 39.5 μg/mL.25