Table 1.

Comparison of patient characteristics in nodal and nonnodal groups




Nodal group

Nonnodal group

P
Patients     
    No.   43   37   
    M/F   2.3/1   2/1   1.0  
    Mean age, y (range)   65 (42-87)   63 (36-81)   .58  
Clinical (%)     
    Splenomegaly   25/43 (58)   28/37 (76)   .15  
    GI tract   8/43 (19)   2/37 (5)   .1  
CD38, 30% or more positive (%)   32/34 (94)   16/33 (48)   < .001  
IgVH genes (%)     
    98% or higher homology   28/31 (90)   15/34 (44)   
    97% homology   3/31 (10)   3/34 (9)   < .001  
    Less than 97% homology   0/31   16/34 (47)   
Karyotype (%)     
    Complex   11/11 (100)   9/17 (53)   .01  
    Single   0/11   8/17 (47)   
Median survival, mo (95% confidence limits)
 
30 (10-50)
 
79 (22-136)
 
.005
 



Nodal group

Nonnodal group

P
Patients     
    No.   43   37   
    M/F   2.3/1   2/1   1.0  
    Mean age, y (range)   65 (42-87)   63 (36-81)   .58  
Clinical (%)     
    Splenomegaly   25/43 (58)   28/37 (76)   .15  
    GI tract   8/43 (19)   2/37 (5)   .1  
CD38, 30% or more positive (%)   32/34 (94)   16/33 (48)   < .001  
IgVH genes (%)     
    98% or higher homology   28/31 (90)   15/34 (44)   
    97% homology   3/31 (10)   3/34 (9)   < .001  
    Less than 97% homology   0/31   16/34 (47)   
Karyotype (%)     
    Complex   11/11 (100)   9/17 (53)   .01  
    Single   0/11   8/17 (47)   
Median survival, mo (95% confidence limits)
 
30 (10-50)
 
79 (22-136)
 
.005
 

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