Circulating levels of cytokines
. | Protein C+/+ . | Protein C+/- . | P . |
|---|---|---|---|
| TNF-α | 231 ± 31 | 842 ± 42 | .01 |
| IL-6 | 1140 ± 192 | 1754 ± 214 | .04 |
| IL-1β | 1244 ± 97 | 1432 ± 85 | .05 |
| IL-10 | 1071 ± 231 | 1196 ± 276 | .1 |
. | Protein C+/+ . | Protein C+/- . | P . |
|---|---|---|---|
| TNF-α | 231 ± 31 | 842 ± 42 | .01 |
| IL-6 | 1140 ± 192 | 1754 ± 214 | .04 |
| IL-1β | 1244 ± 97 | 1432 ± 85 | .05 |
| IL-10 | 1071 ± 231 | 1196 ± 276 | .1 |
Circulating levels of cytokines (pg/mL) in protein-C—deficient mice and wild-type littermates at 4 hours after the administration of endotoxin (n = 6 at each time point in both groups). Values are means ± SD.