Table 1.

Expression of adhesion molecules on CD4+ and CD8+ T cells isolated from healthy controls and MS patients


Lymphocyte subpopulation

Donor

CD162/PSGL-1, % (MFI)

CD11a, % (MFI)

CD62L, % (MFI)

CD49d, % (MFI)
CD4   Healthy   91 ± 4 (138 ± 42)   98 ± 1 (73 ± 10)   66 ± 8 (255 ± 51)   87 ± 8 (19 ± 5)  
CD4   MS   99 ± 0.5 (308 ± 130)   98 ± 0.5 (66 ± 35)   61 ± 19 (305 ± 217)   90 ± 10 (31 ± 24)  
CD8   Healthy   96 ± 3 (235 ± 106)   91 ± 4 (109 ± 26)   49 ± 12 (154 ± 10)   91 ± 17 (31 ± 7)  
CD8
 
MS
 
98 ± 2 (433 ± 125)
 
99 ± 0.5 (128 ± 75)
 
34 ± 19 (145 ± 119)
 
92 ± 18 (41 ± 31)
 

Lymphocyte subpopulation

Donor

CD162/PSGL-1, % (MFI)

CD11a, % (MFI)

CD62L, % (MFI)

CD49d, % (MFI)
CD4   Healthy   91 ± 4 (138 ± 42)   98 ± 1 (73 ± 10)   66 ± 8 (255 ± 51)   87 ± 8 (19 ± 5)  
CD4   MS   99 ± 0.5 (308 ± 130)   98 ± 0.5 (66 ± 35)   61 ± 19 (305 ± 217)   90 ± 10 (31 ± 24)  
CD8   Healthy   96 ± 3 (235 ± 106)   91 ± 4 (109 ± 26)   49 ± 12 (154 ± 10)   91 ± 17 (31 ± 7)  
CD8
 
MS
 
98 ± 2 (433 ± 125)
 
99 ± 0.5 (128 ± 75)
 
34 ± 19 (145 ± 119)
 
92 ± 18 (41 ± 31)
 

Shown are the percentages and MFIs of marker-positive cells in the total population of 4 to 8 experiments.

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