Components of flow scoring system
Points . | Myeloid abnormailities . | Monocytic abnormalities . |
|---|---|---|
| 0 | Appropriate CD45/SSC | Appropriate CD45/SSC |
| Heterogeneous CD11b+, HLA-DR− | CD11b+, heterogeneous HLA-DR | |
| Normal relationships of CD13 and CD16 | CD13/CD16 coexpression | |
| CD33+ | CD33/CD14 coexpression | |
| CD19/CD5/CD34/CD56/CD7− | CD19/CD5/CD34/CD56/CD7− | |
| Synchronous shift to the left | ||
| 1 | One of the following is present: | One of the following is present: |
| Abnormal granularity | Abnormal granularity | |
| Abnormal decrease in CD45 expression | Abnormal CD11b or HLA-DR expression | |
| Presence of HLA-DR or lack of CD11b | Loss of CD13 or CD16 | |
| Convex or abnormal relationship between CD13 and CD16 | Presence of CD56 | |
| Expression of CD56 on subpopulation of myeloid cells | Lack of CD33 or CD14 | |
| Lack of CD33 expression (may be a normal variant) | ||
| Asynchronous shift to the left | ||
| 2 | 2-3 of the above abnormalities or presence of CD34 on myeloid cells or presence of lymphoid antigens on myeloid cells | 2-3 of the above abnormalities or presence of CD34 on monocytes or presence of lymphoid antigens on monocytes (exception is CD4) |
| 3 | 4 or more of the above abnormalities or 1 or more of the abnormalities plus presence of CD34 or lymphoid antigen expression on myeloid cells | 4 or more of the above abnormalities or 1 or more of the abnormalities plus presence of CD34 or lymphoid antigen expression on monocytes |
Points . | Myeloid abnormailities . | Monocytic abnormalities . |
|---|---|---|
| 0 | Appropriate CD45/SSC | Appropriate CD45/SSC |
| Heterogeneous CD11b+, HLA-DR− | CD11b+, heterogeneous HLA-DR | |
| Normal relationships of CD13 and CD16 | CD13/CD16 coexpression | |
| CD33+ | CD33/CD14 coexpression | |
| CD19/CD5/CD34/CD56/CD7− | CD19/CD5/CD34/CD56/CD7− | |
| Synchronous shift to the left | ||
| 1 | One of the following is present: | One of the following is present: |
| Abnormal granularity | Abnormal granularity | |
| Abnormal decrease in CD45 expression | Abnormal CD11b or HLA-DR expression | |
| Presence of HLA-DR or lack of CD11b | Loss of CD13 or CD16 | |
| Convex or abnormal relationship between CD13 and CD16 | Presence of CD56 | |
| Expression of CD56 on subpopulation of myeloid cells | Lack of CD33 or CD14 | |
| Lack of CD33 expression (may be a normal variant) | ||
| Asynchronous shift to the left | ||
| 2 | 2-3 of the above abnormalities or presence of CD34 on myeloid cells or presence of lymphoid antigens on myeloid cells | 2-3 of the above abnormalities or presence of CD34 on monocytes or presence of lymphoid antigens on monocytes (exception is CD4) |
| 3 | 4 or more of the above abnormalities or 1 or more of the abnormalities plus presence of CD34 or lymphoid antigen expression on myeloid cells | 4 or more of the above abnormalities or 1 or more of the abnormalities plus presence of CD34 or lymphoid antigen expression on monocytes |