Clinical presentation by primary diagnosis and primary therapy
Clinical feature . | No. patients . | t-MDS→unknown (%) . | t-MDS (%) . | t-MDS→t-AML (%) . | t-AML (%) . |
|---|---|---|---|---|---|
| Primary diagnosis* | |||||
| No malignancy | 18 | 6 (33) | 3 (17) | 5 (28) | 4 (22) |
| Hematologic malignancy | 171 | 33 (19) | 44 (26) | 61 (36) | 33 (19) |
| Hodgkin disease | 77 | 14 (18) | 13 (17) | 33 (43) | 17 (22) |
| Non-Hodgkin lymphoma | 70 | 12 (17) | 26 (37) | 22 (31) | 10 (14) |
| Myeloma | 23 | 7 (30) | 5 (21) | 6 (26) | 5 (22) |
| Other | 1 | 0 | 0 | 0 | 1 (100) |
| Solid tumor | 117 | 15 (13) | 25 (21) | 32 (27) | 45 (38) |
| Breast | 32 | 4 (13) | 2 (6) | 14 (44) | 12 (38) |
| Ovary | 15 | 1 (7) | 2 (13) | 3 (20) | 9 (60) |
| Prostate | 13 | 2 (15) | 5 (38) | 0 | 6 (46) |
| Lung | 9 | 0 | 2 (22) | 2 (22) | 5 (56) |
| Cervix | 7 | 1 (14) | 3 (43) | 1 (14) | 2 (29) |
| Other | 41 | 7 (17) | 11 (27) | 12 (29) | 11 (27) |
| Totals | 306 | 54 (18) | 72 (24) | 98 (32) | 82 (27) |
| Primary therapy† | |||||
| CT only | 121 | 31 (26) | 26 (21) | 36 (30) | 28 (23) |
| RT only | 43 | 4 (9) | 13 (30) | 11 (26) | 15 (35) |
| CMT | 139 | 19 (14) | 33 (24) | 51 (37) | 36 (26) |
Clinical feature . | No. patients . | t-MDS→unknown (%) . | t-MDS (%) . | t-MDS→t-AML (%) . | t-AML (%) . |
|---|---|---|---|---|---|
| Primary diagnosis* | |||||
| No malignancy | 18 | 6 (33) | 3 (17) | 5 (28) | 4 (22) |
| Hematologic malignancy | 171 | 33 (19) | 44 (26) | 61 (36) | 33 (19) |
| Hodgkin disease | 77 | 14 (18) | 13 (17) | 33 (43) | 17 (22) |
| Non-Hodgkin lymphoma | 70 | 12 (17) | 26 (37) | 22 (31) | 10 (14) |
| Myeloma | 23 | 7 (30) | 5 (21) | 6 (26) | 5 (22) |
| Other | 1 | 0 | 0 | 0 | 1 (100) |
| Solid tumor | 117 | 15 (13) | 25 (21) | 32 (27) | 45 (38) |
| Breast | 32 | 4 (13) | 2 (6) | 14 (44) | 12 (38) |
| Ovary | 15 | 1 (7) | 2 (13) | 3 (20) | 9 (60) |
| Prostate | 13 | 2 (15) | 5 (38) | 0 | 6 (46) |
| Lung | 9 | 0 | 2 (22) | 2 (22) | 5 (56) |
| Cervix | 7 | 1 (14) | 3 (43) | 1 (14) | 2 (29) |
| Other | 41 | 7 (17) | 11 (27) | 12 (29) | 11 (27) |
| Totals | 306 | 54 (18) | 72 (24) | 98 (32) | 82 (27) |
| Primary therapy† | |||||
| CT only | 121 | 31 (26) | 26 (21) | 36 (30) | 28 (23) |
| RT only | 43 | 4 (9) | 13 (30) | 11 (26) | 15 (35) |
| CMT | 139 | 19 (14) | 33 (24) | 51 (37) | 36 (26) |