Table 4. Cytogenetic abnormalities in... | American Society of Hematology

Table 4.

Cytogenetic abnormalities in 306 patients with t-MDS/t-AML

Karyotype	No. (%)
Normal karyotype	24 (8)
Clonal abnormalities	282 (92)
Clonal abnormalities of chromosome 5, 7, or both
(± other abnormalities)	214 (70)
Abnormal chromosome 5^*	63 (21)
Abnormal chromosome 7^*	85 (28)
Abnormal chromosomes 5 and 7	66 (22)
Recurring balanced rearrangements	31 (10)
t(11q23)	10 (3.3)
t(21q22)^*	8 (2.6)
t(15;17)	6 (2.0)
inv(16)^*	6 (2.0)
t(8;16)	1 (0.3)
Other clonal abnormalities	39 (13)†

Karyotype	No. (%)
Normal karyotype	24 (8)
Clonal abnormalities	282 (92)
Clonal abnormalities of chromosome 5, 7, or both
(± other abnormalities)	214 (70)
Abnormal chromosome 5^*	63 (21)
Abnormal chromosome 7^*	85 (28)
Abnormal chromosomes 5 and 7	66 (22)
Recurring balanced rearrangements	31 (10)
t(11q23)	10 (3.3)
t(21q22)^*	8 (2.6)
t(15;17)	6 (2.0)
inv(16)^*	6 (2.0)
t(8;16)	1 (0.3)
Other clonal abnormalities	39 (13)†

One patient with an abnormality of chromosome 5 and t(3;21) and one patient with an abnormality of chromosome 7 and inv(16) are listed twice in the table.

†

Includes eight patients with + 8, 3 patients with − 13/del(13q), and 1 patient each with del(20q), del(11q), + 11, +21, or −Y.

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