Effect of deferiprone on serum ferritin levels
. | . | . | . | . | Mean serum ferritin level, μg/L . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Study . | No. patients . | Length of study, mo . | Dose mg/kg . | Frequency of ferritin assay, wk . | Initial . | Final . | P . | |
| Al-Refaie et al13 | 11 | 6-12 | 85-119 | 12 | 5549 | 4126 | < .05 | |
| Al-Refaie et al*30 | 84 | < 1-48 | 50-100 | NG | 4207 | 1779 | < .01 | |
| Kersten et al32 | 36 | 1-36 | 50-100 | 6-8 | 3563 | 2560 | < .005 | |
| Mazza et al38 | 29 | > 12 | 70 | 4 | 3748 | 2550 | .001 | |
| Olivieri et al19 | 21 | 1.2-4.8 y | 75 | NG | 5759 | 3273 | < .005 | |
| Olivieri et al20 | 18 | 4.6 y | 75 | NG | 4455 | 2831 | < .03 | |
| Hoffbrand et al31 | 26 | 4-49 | 75 | 4 | 2937 | 2323 | NS | |
| Cohen et al39 | 162 | 12 | 75 | 12 | 2579 | 2452 | NS | |
| Maggio et al21 | 71 | 12 | 75 | 4 | 2283 | 2061 | < .05 | |
| Ceci et al40 | 151 | 36 | 75 | 12 | 2579 | 2320 | < .01 | |
. | . | . | . | . | Mean serum ferritin level, μg/L . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Study . | No. patients . | Length of study, mo . | Dose mg/kg . | Frequency of ferritin assay, wk . | Initial . | Final . | P . | |
| Al-Refaie et al13 | 11 | 6-12 | 85-119 | 12 | 5549 | 4126 | < .05 | |
| Al-Refaie et al*30 | 84 | < 1-48 | 50-100 | NG | 4207 | 1779 | < .01 | |
| Kersten et al32 | 36 | 1-36 | 50-100 | 6-8 | 3563 | 2560 | < .005 | |
| Mazza et al38 | 29 | > 12 | 70 | 4 | 3748 | 2550 | .001 | |
| Olivieri et al19 | 21 | 1.2-4.8 y | 75 | NG | 5759 | 3273 | < .005 | |
| Olivieri et al20 | 18 | 4.6 y | 75 | NG | 4455 | 2831 | < .03 | |
| Hoffbrand et al31 | 26 | 4-49 | 75 | 4 | 2937 | 2323 | NS | |
| Cohen et al39 | 162 | 12 | 75 | 12 | 2579 | 2452 | NS | |
| Maggio et al21 | 71 | 12 | 75 | 4 | 2283 | 2061 | < .05 | |
| Ceci et al40 | 151 | 36 | 75 | 12 | 2579 | 2320 | < .01 | |
NG indicates not given; NS, not significant.
A few patients in this study may overlap with patients included in Al-Refaie et al13 and Olivieri et al19 .