Patient characteristics at entry into the study
Characteristic . | No. . |
|---|---|
| Number of patients; male:female | 236; 124:112 |
| Age, y, male:female | |
| 0 to 4 | 152; 79:73 |
| 5 to 9 | 66; 40:26 |
| Older than 9 | 18; 5:13 |
| Median age, mo | 35 |
| Hemoglobin level, g/L, mean±SD | 78±11 |
| Hematocrit level, proportion of 1, mean±SD | .252±.037 |
| Reticulocyte count, proportion of 1, mean±SD | .118±.065 |
| Patients characterized for fetal hemoglobin | 131 |
| Male, %, mean±SD, n = 74 | 10.1±5.8 |
| Female, %, mean±SD, n = 57 | 11.9±5.8 |
| Patients characterized for βs haplotype | 118 |
| Homozygous Benin/Benin | 108 |
| Heterozygous or atypical | 10 |
| Patients characterized for α-globin gene status | 117 |
| αα/αα | 62 |
| αα/α- | 48 |
| α-/α- | 7 |
| Patients characterized for G6PD variant A | 107 |
| Male (patients with A-) | 89 (17) |
| Female (patients with A-) | 18 (8*) |
Characteristic . | No. . |
|---|---|
| Number of patients; male:female | 236; 124:112 |
| Age, y, male:female | |
| 0 to 4 | 152; 79:73 |
| 5 to 9 | 66; 40:26 |
| Older than 9 | 18; 5:13 |
| Median age, mo | 35 |
| Hemoglobin level, g/L, mean±SD | 78±11 |
| Hematocrit level, proportion of 1, mean±SD | .252±.037 |
| Reticulocyte count, proportion of 1, mean±SD | .118±.065 |
| Patients characterized for fetal hemoglobin | 131 |
| Male, %, mean±SD, n = 74 | 10.1±5.8 |
| Female, %, mean±SD, n = 57 | 11.9±5.8 |
| Patients characterized for βs haplotype | 118 |
| Homozygous Benin/Benin | 108 |
| Heterozygous or atypical | 10 |
| Patients characterized for α-globin gene status | 117 |
| αα/αα | 62 |
| αα/α- | 48 |
| α-/α- | 7 |
| Patients characterized for G6PD variant A | 107 |
| Male (patients with A-) | 89 (17) |
| Female (patients with A-) | 18 (8*) |
One female patient was homozygous A-/A-