Table 1.

PIGF induces THP-1 monocyte chemotaxis


Checkerboard analysis

Upper compartment PIGF (nM)
Lower compartment (PIGF nM)   None   0.5   1.0   2.5   5.0  
None   12.0   24.0   36.0   38.0   34.0  
0.5   48.0   145.0   117.0   46.0   56.0  
5.0
 
312.0
 
262.0
 
270.0
 
90.0
 
62.0
 

Checkerboard analysis

Upper compartment PIGF (nM)
Lower compartment (PIGF nM)   None   0.5   1.0   2.5   5.0  
None   12.0   24.0   36.0   38.0   34.0  
0.5   48.0   145.0   117.0   46.0   56.0  
5.0
 
312.0
 
262.0
 
270.0
 
90.0
 
62.0
 

Different concentrations of PIGF were added to the upper and/or lower compartments of the Neuro Probe chamber. The number of migrated cells were counted for each sample after 2 hours. Data from a representative experiment are shown.

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