Relative and absolute T-cell numbers in B-CLL
. | CD19 . | CD3 . | CD3 CD4 . | CD3 CD8 . |
---|---|---|---|---|
Control, n = 12 | ||||
% | 13±5 | 63±12 | 55±17 | 19±10 |
No. | 311±152 | 1461±481 | 805±365 | 285±171 |
Rai 0, n = 12 | ||||
% | 78±13* | 15±11* | 55±18 | 35±18† |
No. | 19 280±20 090* | 2124±814‡ | 1101±521 | 830±597* |
Rai I-II, n = 10 | ||||
% | 81±9* | 13±6* | 44±23 | 33±16‡ |
No. | 20 800±15 770* | 2794±1414† | 1316±983 | 865±499† |
Rai III-IV, n = 6 | ||||
% | 90±8* | 5±5* | 39±22 | 44±24† |
No. | 68 000±46 220* | 2568±1179† | 1183±1065 | 1008±394† |
. | CD19 . | CD3 . | CD3 CD4 . | CD3 CD8 . |
---|---|---|---|---|
Control, n = 12 | ||||
% | 13±5 | 63±12 | 55±17 | 19±10 |
No. | 311±152 | 1461±481 | 805±365 | 285±171 |
Rai 0, n = 12 | ||||
% | 78±13* | 15±11* | 55±18 | 35±18† |
No. | 19 280±20 090* | 2124±814‡ | 1101±521 | 830±597* |
Rai I-II, n = 10 | ||||
% | 81±9* | 13±6* | 44±23 | 33±16‡ |
No. | 20 800±15 770* | 2794±1414† | 1316±983 | 865±499† |
Rai III-IV, n = 6 | ||||
% | 90±8* | 5±5* | 39±22 | 44±24† |
No. | 68 000±46 220* | 2568±1179† | 1183±1065 | 1008±394† |
Distribution of B cells and subsets of T cells in controls and B-CLL patients of different Rai stages. Mean ± SD of relative (%) and absolute (no. of cells/μL) numbers are presented. Numbers of CD4+ and CD8+ cells were detected within the CD3+ gate. The relative number of CD3+ T cells was increased due to elevated numbers of CD8+ T cells in all Rai stages of B-CLL
Significantly different from controls, P < .001
Significantly different from controls, P < .01
Significantly different from controls, P < .05