Table 1.

Relative and absolute T-cell numbers in B-CLL




CD19

CD3

CD3 CD4

CD3 CD8
Control, n = 12      
    %   13±5   63±12   55±17   19±10  
    No.   311±152   1461±481   805±365   285±171  
Rai 0, n = 12      
    %   78±13*  15±11*  55±18   35±18 
    No.   19 280±20 090*  2124±814  1101±521   830±597* 
Rai I-II, n = 10      
    %   81±9*  13±6*  44±23   33±16 
    No.   20 800±15 770*  2794±1414  1316±983   865±499 
Rai III-IV, n = 6      
    %   90±8*  5±5*  39±22   44±24 
    No.
 
68 000±46 220*
 
2568±1179
 
1183±1065
 
1008±394
 



CD19

CD3

CD3 CD4

CD3 CD8
Control, n = 12      
    %   13±5   63±12   55±17   19±10  
    No.   311±152   1461±481   805±365   285±171  
Rai 0, n = 12      
    %   78±13*  15±11*  55±18   35±18 
    No.   19 280±20 090*  2124±814  1101±521   830±597* 
Rai I-II, n = 10      
    %   81±9*  13±6*  44±23   33±16 
    No.   20 800±15 770*  2794±1414  1316±983   865±499 
Rai III-IV, n = 6      
    %   90±8*  5±5*  39±22   44±24 
    No.
 
68 000±46 220*
 
2568±1179
 
1183±1065
 
1008±394
 

Distribution of B cells and subsets of T cells in controls and B-CLL patients of different Rai stages. Mean ± SD of relative (%) and absolute (no. of cells/μL) numbers are presented. Numbers of CD4+ and CD8+ cells were detected within the CD3+ gate. The relative number of CD3+ T cells was increased due to elevated numbers of CD8+ T cells in all Rai stages of B-CLL

*

Significantly different from controls, P < .001

Significantly different from controls, P < .01

Significantly different from controls, P < .05

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