Decreased expression of NKRs on CD8+CD45RA+CD27- cytotoxic T cells in B-CLL
. | NKB-1 . | CD94 . | CD158a . | CD158b . |
|---|---|---|---|---|
| Control, n = 9 | ||||
| CD8+ | 3±1 | 11±3 | 4±2 | 5±1 |
| CD8+CD45RA+CD27- | 13±3 | 29±8 | 11±1 | 21±3 |
| B-CLL, n = 18 | ||||
| CD8+ | 3±0.6 | 8±2 | 2±0.3 | 7±2 |
| CD8+CD45RA+CD27- | 4±1* | 14±4 | 5±1† | 12±3* |
. | NKB-1 . | CD94 . | CD158a . | CD158b . |
|---|---|---|---|---|
| Control, n = 9 | ||||
| CD8+ | 3±1 | 11±3 | 4±2 | 5±1 |
| CD8+CD45RA+CD27- | 13±3 | 29±8 | 11±1 | 21±3 |
| B-CLL, n = 18 | ||||
| CD8+ | 3±0.6 | 8±2 | 2±0.3 | 7±2 |
| CD8+CD45RA+CD27- | 4±1* | 14±4 | 5±1† | 12±3* |
Expression of the NKRs NKB-1, CD94, CD158a, and CD158b was analyzed on different CD8+ T-cell subsets in a 4-color immunostaining combining CD27-FITC, CD8-PercP, CD45RA-bio-Strep-APC, and PE-labeled α-NKR antibodies. Mean ± SEM of the percentage of cells is indicated
Significantly different from controls, P < .05
Significantly different from controls, P < .01