Table 1.

Effects of sera from MM patients' BM on phenotype of DCs



Concentration of cytokines*

% Positivity

IL-6, pg/mL
VEGF, pg/mL
CD14
CD1a
CD80
CD83
MM Pt BM   47.0   1061   31.1   22.1   17.5   9.2  
AB serum
 
<4.7
 
180
 
7.7
 
55.1
 
55.8
 
48.8
 


Concentration of cytokines*

% Positivity

IL-6, pg/mL
VEGF, pg/mL
CD14
CD1a
CD80
CD83
MM Pt BM   47.0   1061   31.1   22.1   17.5   9.2  
AB serum
 
<4.7
 
180
 
7.7
 
55.1
 
55.8
 
48.8
 
*

Results shown are the mean of BM sera from 10 MM patients in duplicate experiments. Values below the detectability by ELISA (4.7 pg/mL for IL-6 and 62.5 pg/mL for VEGF) were read as 0 to calculate the mean.

Percentages of positive cells compared with isotype-matched control antibody are shown.

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