Table 1.

Withdrawals due to adverse events


Adverse event

Year 1, no. patients (% patients)

Years 2 to 4, no. patients (% patients)
Neutropenia   9 (4.8)   6 (3.2)  
Other   4 (2.1)*  1 (0.5) 
Nausea/vomiting   3 (1.6)   0  
Thrombocytopenia   2 (1.1)   0  
Agranulocytosis   1 (0.5)   0  
Increased ALT level   1 (0.5)   0  
Hepatitis   1 (0.5)   0  
Arthropathy
 
0
 
1 (0.5)
 

Adverse event

Year 1, no. patients (% patients)

Years 2 to 4, no. patients (% patients)
Neutropenia   9 (4.8)   6 (3.2)  
Other   4 (2.1)*  1 (0.5) 
Nausea/vomiting   3 (1.6)   0  
Thrombocytopenia   2 (1.1)   0  
Agranulocytosis   1 (0.5)   0  
Increased ALT level   1 (0.5)   0  
Hepatitis   1 (0.5)   0  
Arthropathy
 
0
 
1 (0.5)
 
*

Hypersplenism (1), asthenia (1), and decreased neutrophil count (but not meeting criteria for neutropenia) (2).

Depression.

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