Table 1.

Decreased thymocyte number in tachykinin antagonist-treated mice


Treatment, no. individual mice analyzed


Fractionated thymocytes, × 104
Total thymocytes, × 105
CD4+CD8+
CD4+CD8-
CD4-CD8+
CD4-CD8-
No treatment, n = 4   410 ± 100   3300 ± 600   460 ± 290   140 ± 70   200 ± 80  
DMSO solvent, n = 4   370 ± 150   2900 ± 1300   380 ± 130   140 ± 70   190 ± 80  
Antagonist, n = 6*
 
9 ± 16
 
5 ± 9
 
53 ± 92
 
27 ± 50
 
9 ± 10
 

Treatment, no. individual mice analyzed


Fractionated thymocytes, × 104
Total thymocytes, × 105
CD4+CD8+
CD4+CD8-
CD4-CD8+
CD4-CD8-
No treatment, n = 4   410 ± 100   3300 ± 600   460 ± 290   140 ± 70   200 ± 80  
DMSO solvent, n = 4   370 ± 150   2900 ± 1300   380 ± 130   140 ± 70   190 ± 80  
Antagonist, n = 6*
 
9 ± 16
 
5 ± 9
 
53 ± 92
 
27 ± 50
 
9 ± 10
 

All data are given as the mean ± standard deviation (SD) per lobe.

*

P < .05 with paired, 2-tailed t tests between solvent and antagonist.

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