Univariate matched odds ratios for a first spontaneous abortion between 8 and 10 weeks of pregnancy by antihemostasis-related key glycoproteins antibodies
Biomarker . | Case patients (%) n = 743 . | Control patients (%) n = 743 . | Matched odds ratio . | 95% confidence interval . | P* . |
|---|---|---|---|---|---|
| Antitissue-type plasminogen activator IgG by percentiles | <.001 | ||||
| 1-80 | 235 (31.6) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 360 (48.5) | 111 (15.0) | 8.5 | 6.1-11.8 | |
| 96-99 | 82 (11.0) | 29 (3.9) | 8.4 | 5.0-14.1 | |
| 100 | 66 (8.9) | 7 (1.0) | 21.2 | 9.5-47.4 | |
| Antitissue-type plasminogen activator IgM by percentiles | .47 | ||||
| 1-80 | 580 (78.1) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 128 (17.2) | 112 (15.1) | 1.2 | 0.9-1.6 | |
| 96-99 | 28 (3.8) | 28 (3.8) | 1.0 | 0.6-1.8 | |
| 100 | 7 (1.0) | 7 (1.0) | 1.0 | 0.4-2.9 | |
| Antitissue factor IgG by percentiles | .54 | ||||
| 1-80 | 594 (80.0) | 595 (80.0) | 1.0 | Reference | |
| 81-95 | 107 (14.4) | 111 (14.9) | 1.0 | 0.7-1.3 | |
| 96-99 | 27 (3.6) | 30 (4.0) | 0.9 | 0.5-1.5 | |
| 100 | 15 (2.0) | 7 (1.0) | 2.1 | 0.9-5.2 | |
| Antitissue factor IgM by percentiles | .40 | ||||
| 1-80 | 577 (77.6) | 595 (80.1) | 1.0 | Reference | |
| 81-95 | 126 (1.0) | 111 (14.9) | 1.2 | 0.9-1.5 | |
| 96-99 | 35 (4.7) | 30 (4.0) | 1.2 | 0.7-2.0 | |
| 100 | 5 (0.7) | 7 (1.0) | 0.7 | 0.2-2.3 | |
| Antithrombomodulin IgG by percentiles | .001 | ||||
| 1-80 | 576 (77.5) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 90 (12.1) | 111 (14.9) | 0.8 | 0.6-1.1 | |
| 96-99 | 41 (5.5) | 29 (3.9) | 1.4 | 0.9-2.3 | |
| 100 | 36 (4.8) | 7 (1.0) | 5.7 | 2.4-13.7 | |
| Antithrombomodulin IgM by percentiles | .59 | ||||
| 1-80 | 585 (78.7) | 597 (80.3) | 1.0 | Reference | |
| 81-95 | 122 (16.4) | 108 (14.5) | 1.1 | 0.9-1.5 | |
| 96-99 | 29 (3.9) | 31 (4.2) | 1.0 | 0.6-1.6 | |
| 100 | 7 (1.0) | 7 (1.0) | 1.0 | 0.4-2.9 |
Biomarker . | Case patients (%) n = 743 . | Control patients (%) n = 743 . | Matched odds ratio . | 95% confidence interval . | P* . |
|---|---|---|---|---|---|
| Antitissue-type plasminogen activator IgG by percentiles | <.001 | ||||
| 1-80 | 235 (31.6) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 360 (48.5) | 111 (15.0) | 8.5 | 6.1-11.8 | |
| 96-99 | 82 (11.0) | 29 (3.9) | 8.4 | 5.0-14.1 | |
| 100 | 66 (8.9) | 7 (1.0) | 21.2 | 9.5-47.4 | |
| Antitissue-type plasminogen activator IgM by percentiles | .47 | ||||
| 1-80 | 580 (78.1) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 128 (17.2) | 112 (15.1) | 1.2 | 0.9-1.6 | |
| 96-99 | 28 (3.8) | 28 (3.8) | 1.0 | 0.6-1.8 | |
| 100 | 7 (1.0) | 7 (1.0) | 1.0 | 0.4-2.9 | |
| Antitissue factor IgG by percentiles | .54 | ||||
| 1-80 | 594 (80.0) | 595 (80.0) | 1.0 | Reference | |
| 81-95 | 107 (14.4) | 111 (14.9) | 1.0 | 0.7-1.3 | |
| 96-99 | 27 (3.6) | 30 (4.0) | 0.9 | 0.5-1.5 | |
| 100 | 15 (2.0) | 7 (1.0) | 2.1 | 0.9-5.2 | |
| Antitissue factor IgM by percentiles | .40 | ||||
| 1-80 | 577 (77.6) | 595 (80.1) | 1.0 | Reference | |
| 81-95 | 126 (1.0) | 111 (14.9) | 1.2 | 0.9-1.5 | |
| 96-99 | 35 (4.7) | 30 (4.0) | 1.2 | 0.7-2.0 | |
| 100 | 5 (0.7) | 7 (1.0) | 0.7 | 0.2-2.3 | |
| Antithrombomodulin IgG by percentiles | .001 | ||||
| 1-80 | 576 (77.5) | 596 (80.2) | 1.0 | Reference | |
| 81-95 | 90 (12.1) | 111 (14.9) | 0.8 | 0.6-1.1 | |
| 96-99 | 41 (5.5) | 29 (3.9) | 1.4 | 0.9-2.3 | |
| 100 | 36 (4.8) | 7 (1.0) | 5.7 | 2.4-13.7 | |
| Antithrombomodulin IgM by percentiles | .59 | ||||
| 1-80 | 585 (78.7) | 597 (80.3) | 1.0 | Reference | |
| 81-95 | 122 (16.4) | 108 (14.5) | 1.1 | 0.9-1.5 | |
| 96-99 | 29 (3.9) | 31 (4.2) | 1.0 | 0.6-1.6 | |
| 100 | 7 (1.0) | 7 (1.0) | 1.0 | 0.4-2.9 |
All the variables are divided into 4 categories: percentiles 1-80, 81-95, 96-99, and 100.
P was determined for linear trend.