Table 3.

Calculated median radiation absorbed dose (cGy) of target and nontarget organs according to intended 166Ho-DOTMP dose level

Nontarget organ
Without TBI
With TBI
20 Gy
30 Gy
40 Gy
20 Gy
30 Gy
40 Gy
Bone   3850   4950   6785   4440   5250   7480  
Bone marrow*  2070   2420   3850   2605   3360   4875  
Bladder wal†  4110   2600   3900   5110   5930   9255  
Kidney   260   370   550   1100   1170   1385  
Liver   60   90   110   880   890   935  
Lung
 		 60
 		 90
 		 110
 		 880
 		 890
 		 935
 
Nontarget organ
Without TBI
With TBI
20 Gy
30 Gy
40 Gy
20 Gy
30 Gy
40 Gy
Bone   3850   4950   6785   4440   5250   7480  
Bone marrow*  2070   2420   3850   2605   3360   4875  
Bladder wal†  4110   2600   3900   5110   5930   9255  
Kidney   260   370   550   1100   1170   1385  
Liver   60   90   110   880   890   935  
Lung
 		 60
 		 90
 		 110
 		 880
 		 890
 		 935
 
*

These median values include adjustment for patient size for bone marrow dose.

†

These median values include patients with and without bladder irrigation.

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