Bearman grades 1 to 2 early toxicities (less than 60 days after transplantation) by nominal dose level
Toxicity grade . | 20 Gy, n (%) . | 30 Gy, n (%) . | 40 Gy, n (%) . | All doses, n (%) . |
|---|---|---|---|---|
| Cardiac | ||||
| Grade 1 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Grade 2 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Bladder | ||||
| Grade 1 | 0 | 0 | 3 (6.3) | 3 (3.6) |
| Grade 2 | 0 | 1 (5) | 0 | 1 (1.2) |
| Pulmonary | ||||
| Grade 1 | 0 | 0 | 3 (6.3) | 3 (3.6) |
| Grade 2 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Hepatic | ||||
| Grade 1 | 6 (40) | 6 (30) | 18 (37.5) | 30 (36.1) |
| Grade 2 | 4 (26.7) | 7 (35) | 12 (25) | 23 (27.7) |
| Stomatitis | ||||
| Grade 1 | 13 (86.7) | 9 (45) | 25 (52.1) | 47 (56.6) |
| Grade 2 | 0 | 8 (40) | 15 (31.25) | 23 (27.7) |
| Gastrointestinal | ||||
| Grade 1 | 6 (40) | 8 (40) | 19 (39.6) | 33 (39.7) |
| Grade 2 | 0 | 1 (5) | 2 (4.2) | 3 (3.6) |
| Renal | ||||
| Grade 1 | 0 | 1 (5) | 1 (2.1) | 2 (2.4) |
| Grade 2 | 0 | 2 (10) | 2 (4.2) | 4 (4.8) |
| CNS | ||||
| Grade 1 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Grade 2 | 0 | 1 (5) | 1 (2.1) | 2 (2.4) |
Toxicity grade . | 20 Gy, n (%) . | 30 Gy, n (%) . | 40 Gy, n (%) . | All doses, n (%) . |
|---|---|---|---|---|
| Cardiac | ||||
| Grade 1 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Grade 2 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Bladder | ||||
| Grade 1 | 0 | 0 | 3 (6.3) | 3 (3.6) |
| Grade 2 | 0 | 1 (5) | 0 | 1 (1.2) |
| Pulmonary | ||||
| Grade 1 | 0 | 0 | 3 (6.3) | 3 (3.6) |
| Grade 2 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Hepatic | ||||
| Grade 1 | 6 (40) | 6 (30) | 18 (37.5) | 30 (36.1) |
| Grade 2 | 4 (26.7) | 7 (35) | 12 (25) | 23 (27.7) |
| Stomatitis | ||||
| Grade 1 | 13 (86.7) | 9 (45) | 25 (52.1) | 47 (56.6) |
| Grade 2 | 0 | 8 (40) | 15 (31.25) | 23 (27.7) |
| Gastrointestinal | ||||
| Grade 1 | 6 (40) | 8 (40) | 19 (39.6) | 33 (39.7) |
| Grade 2 | 0 | 1 (5) | 2 (4.2) | 3 (3.6) |
| Renal | ||||
| Grade 1 | 0 | 1 (5) | 1 (2.1) | 2 (2.4) |
| Grade 2 | 0 | 2 (10) | 2 (4.2) | 4 (4.8) |
| CNS | ||||
| Grade 1 | 0 | 0 | 1 (2.1) | 1 (1.2) |
| Grade 2 | 0 | 1 (5) | 1 (2.1) | 2 (2.4) |
Patient populations by toxicity group: 20 Gy, n = 15; 30 Gy, n = 20; 40 Gy, n = 48; and all doses, n = 83.
CNS indicates central nervous system.