Table 1.

Patient characteristics, N = 201


Characteristic

n (%)
Underlying disease  
    Lymphoma   12 (6.0)  
    Acute leukemia   59 (29.4)  
    Chronic leukemia   95 (47.3)  
    Aplastic anemia   11 (5.5)  
    Myelodysplastic syndrome   19 (9.5)  
    Miscellaneous   5 (2.5)  
Source of stem cells  
    Bone marrow   169 (84.1)  
    Peripheral mobilized stem cell   32 (15.9)  
Age, y; median (range)   40 (2-66)  
Sex  
    Male   116 (57.7)  
    Female   85 (42.3)  
Transplant type  
    Matched related   133 (66.2)  
    Mismatched/unrelated   68 (33.8)  
Total body irradiation conditioning   105 (52.2)  
Received ganciclovir  
    Yes   154 (76.6)  
    No   46 (22.9)  
    Data not available   1 (0.5)  
Steroid use*  
    None   77 (39.1)  
    Between 0 and 1 mg/kg/d   62 (31.5)  
    At least 2 mg/kg/d   58 (29.4)  
GVHD  
    Grade 0 to 1   62 (30.9)  
    Grade II   103 (51.2)  
    At least grade III   36 (17.9)  
Donor CMV serology  
    Positive   131 (65.2)  
    Negative
 
70 (34.8)
 

Characteristic

n (%)
Underlying disease  
    Lymphoma   12 (6.0)  
    Acute leukemia   59 (29.4)  
    Chronic leukemia   95 (47.3)  
    Aplastic anemia   11 (5.5)  
    Myelodysplastic syndrome   19 (9.5)  
    Miscellaneous   5 (2.5)  
Source of stem cells  
    Bone marrow   169 (84.1)  
    Peripheral mobilized stem cell   32 (15.9)  
Age, y; median (range)   40 (2-66)  
Sex  
    Male   116 (57.7)  
    Female   85 (42.3)  
Transplant type  
    Matched related   133 (66.2)  
    Mismatched/unrelated   68 (33.8)  
Total body irradiation conditioning   105 (52.2)  
Received ganciclovir  
    Yes   154 (76.6)  
    No   46 (22.9)  
    Data not available   1 (0.5)  
Steroid use*  
    None   77 (39.1)  
    Between 0 and 1 mg/kg/d   62 (31.5)  
    At least 2 mg/kg/d   58 (29.4)  
GVHD  
    Grade 0 to 1   62 (30.9)  
    Grade II   103 (51.2)  
    At least grade III   36 (17.9)  
Donor CMV serology  
    Positive   131 (65.2)  
    Negative
 
70 (34.8)
 
*

An accurate assessment of steroid dose could not be performed for 4 patients.

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