Association of pretreatment variables with response in validation cohort
Pretreatment variable . | Association with response in univariate analyses, P* . | Association with response in multivariate analyses, P† . |
|---|---|---|
| PPR, n = 23 | .002 | .009 |
| Age, n = 23 | .02 | .77 |
| Presence of PNH by flow cytometry, n = 5/23 | .007 | .35 |
| Blasts less than 5%, n = 19/23 | .21 | — |
| Duration of RCTD, n = 23 | .49 | — |
| HLA DR15+, n = 8/23 | .14 | — |
| Normal cytogenetics, n = 15/21 | .46 | — |
| Hypocellular bone marrow, n = 2/23 | .79 | — |
| Tricytopenia, n = 2/23 | .10 | — |
Pretreatment variable . | Association with response in univariate analyses, P* . | Association with response in multivariate analyses, P† . |
|---|---|---|
| PPR, n = 23 | .002 | .009 |
| Age, n = 23 | .02 | .77 |
| Presence of PNH by flow cytometry, n = 5/23 | .007 | .35 |
| Blasts less than 5%, n = 19/23 | .21 | — |
| Duration of RCTD, n = 23 | .49 | — |
| HLA DR15+, n = 8/23 | .14 | — |
| Normal cytogenetics, n = 15/21 | .46 | — |
| Hypocellular bone marrow, n = 2/23 | .79 | — |
| Tricytopenia, n = 2/23 | .10 | — |