Table 3. LMP2A-expressing cells and... | American Society of Hematology

Table 3.

LMP2A-expressing cells and Hodgkin lymphoma

Gene^*	Expression	Tissue†	Reference no.
B-cell factors/signaling
E2A (E47)	Decreased	BM, spleen	30
Early B-cell factor (EBF)	Decreased	BM, spleen	30
Pax-5 (BSAP)	Decreased	BM, spleen	30,31
PU.1	Decreased	BM	30,32,33
Ig-α (Mb-1)	Decreased	BM, spleen	33,34
Rag2	Decreased	BM	35
CD19	Decreased	Spleen	33,34
CD22	Decreased	Spleen	33,34
Blk	Decreased	Spleen	33,34
SWAP70	Decreased	Spleen	33,34
Syk	Decreased	BM	34
Blnk	Decreased	Spleen	33
Spi-B	Decreased	Spleen	33
CD20	Decreased	LCL	33
LFA-1	Decreased	BJAB	33
Igk	Decreased	BJAB	33
Cell cycle/apoptosis
Ki67	Increased	Spleen	36
Cyclin A	Increased	Spleen	37
PCNA	Increased	BM	38
Bcl-xL	Increased	Spleen	37
Survivin	Increased	BM, spleen	37
Bcl-6	Decreased	Spleen	34
Immunity
IL-5	Increased	BM	39
IL-13R	Increased	Spleen	40
EB13	Increased	Spleen	41

Gene^*	Expression	Tissue†	Reference no.
B-cell factors/signaling
E2A (E47)	Decreased	BM, spleen	30
Early B-cell factor (EBF)	Decreased	BM, spleen	30
Pax-5 (BSAP)	Decreased	BM, spleen	30,31
PU.1	Decreased	BM	30,32,33
Ig-α (Mb-1)	Decreased	BM, spleen	33,34
Rag2	Decreased	BM	35
CD19	Decreased	Spleen	33,34
CD22	Decreased	Spleen	33,34
Blk	Decreased	Spleen	33,34
SWAP70	Decreased	Spleen	33,34
Syk	Decreased	BM	34
Blnk	Decreased	Spleen	33
Spi-B	Decreased	Spleen	33
CD20	Decreased	LCL	33
LFA-1	Decreased	BJAB	33
Igk	Decreased	BJAB	33
Cell cycle/apoptosis
Ki67	Increased	Spleen	36
Cyclin A	Increased	Spleen	37
PCNA	Increased	BM	38
Bcl-xL	Increased	Spleen	37
Survivin	Increased	BM, spleen	37
Bcl-6	Decreased	Spleen	34
Immunity
IL-5	Increased	BM	39
IL-13R	Increased	Spleen	40
EB13	Increased	Spleen	41

Genes listed are similarly expressed in LMP2A-expressing cells and Hodgkin lymphoma cell lines or HRS cells.

Lists the tissue types in which gene expression was affected in LMP2A transgenic mice.