Table 3. Genes with a frequency of 1 and... | American Society of Hematology

Table 3.

Genes with a frequency of 1 and differentially regulated upon exposure to Epo/SCF/Dex or Epo/SCF/ZK for 2, 6, 18, or 24 hours, including their regulation in GR^dim/dim versus wt erythroid progenitors

		2 hours			6 hours			18 hours			24 hours
Accession no.	Gene description	First	Second	First	Second	First	Second	First	Second	First	Second
Dex up-regulated
*AA020552*	*IMAGE:455550 5*	*0.86*	*1.20*	*1.15*	*1.27*	*1.70*	*2.12*	*1.56*	*3.44*	*1.11*	*2.10*
AW553415	Mouse newborn ovary cDNA library	0.70	1.60	0.76	0.80	1.10	1.70	2.02	2.06	0.61	1.03
*NM_007475*	*Acidic ribosomal phosphoprotein PO*	*0.88*	*1.36*	*2.20*	*2.55*	*1.50*	*1.41*	*1.78*	*1.43*	*0.69*	*0.77*
NM_025840	Basic leucine zipper and W2 domains 2	0.77	1.46	1.02	1.07	0.69	1.96	2.05	2.31	0.48	0.93
*AK003679*	*RIKEN:1110014C11*	*0.91*	*1.33*	*1.13*	*1.25*	*0.94*	*1.57*	*1.95*	*2.88*	*0.76*	*0.91*
D87747	CXCR-4	1.07	1.66	1.51	1.29	1.16	1.18	1.58	1.90	0.91	1.15
*NM_011722*	*Dynactin 6*	*1.29*	*1.28*	*1.87*	*1.96*	*1.25*	*3.00*	*2.88*	*4.64*	*0.68*	*0.89*
BC005660	Eukaryotic translation elongation factor 1 alpha 1	0.72	1.36	1.06	0.92	0.88	1.46	2.13	2.27	0.52	0.89
*BG080849*	*CDNA clone H3058D01-5*	*0.78*	*1.55*	*1.92*	*1.62*	*1.01*	*0.70*	*0.74*	*0.94*	*0.62*	*0.80*
AA655703	IMAGE:1149396	0.78	1.49	2.03	2.03	0.90	1.17	1.70	2.42	0.94	1.17
*BE630992*	*IMAGE:3375525*	*1.25*	*0.81*	*2.10*	*2.06*	*1.90*	*1.79*	*1.26*	*1.15*	*0.88*	*0.83*
AK020317	RIKEN 9230106805	1.21	0.74	1.52	1.93	2.93	1.79	1.02	1.84	0.74	0.64
*NM_021099*	*kit oncogene*	*1.32*	*1.02*	*1.09*	*1.23*	*2.12*	*4.71*	*2.06*	*3.61*	*0.60*	*0.53*
BC006720	Karyopherin (importin) alpha 2	0.62	1.42	0.99	0.86	0.57	0.93	1.61	1.55	0.67	1.56
*K02061*	*L32-4A pseudogene*	*0.96*	*1.20*	*1.13*	*1.01*	*1.42*	*1.52*	*1.88*	*3.30*	*0.57*	*0.75*
NM_010686	Laptm5	1.17	0.77	1.14	1.36	2.04	3.88	1.40	0.98	2.34	1.37
*NM_010708*	*Lectin, galactose binding, soluble 9*	*1.08*	*0.73*	*0.80*	*0.81*	*1.49*	*2.67*	*1.56*	*3.06*	*1.20*	*0.85*
NM_020573	Oxysterol binding proteinlike 1A	0.88	1.10	1.10	1.14	1.21	1.71	1.98	2.14	0.99	1.09
*BC005779*	*RIKEN cDNA 0610010E03 gene*	*0.75*	*1.21*	*1.20*	*0.93*	*0.87*	*1.16*	*1.67*	*1.93*	*0.57*	*0.91*
AK002923	RIKEN cDNA 0610043A03 gene	0.97	1.10	1.45	1.21	1.74	2.04	1.61	2.92	0.55	0.78
*AK004571*	*RIKEN cDNA 1200003I10 gene*	*0.82*	*1.47*	*1.65*	*1.65*	*0.57*	*1.02*	*2.15*	*2.11*	*0.71*	*1.38*
NM_023270	RIKEN cDNA 1300002C13 gene	1.36	1.04	1.15	1.42	1.22	1.27	1.57	2.30	0.96	0.67
*AK010014*	*RIKEN cDNA 2310061N23 gene*	*0.87*	*1.44*	*2.15*	*2.27*	*2.16*	*1.00*	*1.15*	*1.49*	*0.70*	*0.78*
NM_011291	Similar to ribosomal protein L7	0.93	1.10	1.18	1.12	1.19	1.67	1.61	3.17	1.09	0.97
*NM_016959*	*Ribosomal protein S3a (Rps3a)*	*1.41*	*0.68*	*1.03*	*1.12*	*1.54*	*1.74*	*1.35*	*3.15*	*1.05*	*0.45*
NM_009096	Ribosomal protein S6 (Rps6)	1.50	0.74	1.08	1.01	1.56	1.68	1.37	4.36	1.05	0.46
*NM_011300*	*Similar to ribosomal protein S7*	*0.94*	*1.22*	*1.03*	*1.03*	*1.00*	*1.13*	*1.55*	*2.50*	*0.78*	*0.95*
NM_023380	Samsn1	1.18	0.84	1.15	1.46	1.58	1.61	1.57	3.02	0.64	0.59
*NM_026506*	*Small nuclear ribonucleoprotein polypeptide G*	*0.65*	*1.31*	*1.21*	*0.81*	*0.75*	*1.37*	*1.87*	*2.49*	*0.37*	*0.57*
D13695	ST2L protein	0.72	1.51	1.69	2.05	0.78	1.08	1.92	1.04	0.58	1.19
*AA199458*	*UDP-glucose ceramide glucosyltransferase*	*0.91*	*1.61*	*1.63*	*2.23*	*0.87*	*1.01*	*3.00*	*3.03*	*0.65*	*1.01*
Dex repressed
*AK010947*	*RIKEN clone 2510009J19*	*1.37*	*0.57*	*0.89*	*0.69*	*0.99*	*0.42*	*0.50*	*0.64*	*2.32*	*1.30*
BC005803	IMAGE:3154023	1.14	0.78	0.84	0.84	1.76	1.46	0.57	0.52	1.25	1.08
*BC006617*	*IMAGE:3967600*	*1.48*	*0.92*	*1.20*	*1.01*	*1.30*	*0.72*	*0.57*	*0.51*	*0.88*	*0.63*
AF290209	Podocalyxin	1.12	1.81	0.57	0.54	1.13	1.24	1.60	1.90	9.41	7.04
*NM_030680*	*Regulator of nonsense transcripts 1*	*1.22*	*1.04*	*0.89*	*0.75*	*0.86*	*0.41*	*0.49*	*0.60*	*1.87*	*1.44*
AK003374	RIKEN clone 1110003L06	1.13	0.89	0.86	0.77	0.84	0.48	0.54	0.64	1.63	1.59
*AK010608*	*RIKEN clone:2410029N08*	*1.46*	*0.87*	*1.30*	*0.91*	*1.43*	*0.41*	*0.58*	*0.46*	*1.48*	*1.06*
NM_011403	Solute carrier family 4 (anion exchanger), Slc4a1	1.32	0.93	0.65	1.05	0.83	0.49	0.61	0.48	2.02	1.28
*NM_031878*	*Smarcd2*	*1.67*	*0.72*	*0.92*	*0.77*	*1.04*	*0.52*	*0.53*	*0.64*	*2.35*	*1.25*
U69135	UCP2	0.71	1.49	1.03	0.80	1.33	1.37	0.58	0.26	1.67	2.46

		2 hours			6 hours			18 hours			24 hours
Accession no.	Gene description	First	Second	First	Second	First	Second	First	Second	First	Second
Dex up-regulated
*AA020552*	*IMAGE:455550 5*	*0.86*	*1.20*	*1.15*	*1.27*	*1.70*	*2.12*	*1.56*	*3.44*	*1.11*	*2.10*
AW553415	Mouse newborn ovary cDNA library	0.70	1.60	0.76	0.80	1.10	1.70	2.02	2.06	0.61	1.03
*NM_007475*	*Acidic ribosomal phosphoprotein PO*	*0.88*	*1.36*	*2.20*	*2.55*	*1.50*	*1.41*	*1.78*	*1.43*	*0.69*	*0.77*
NM_025840	Basic leucine zipper and W2 domains 2	0.77	1.46	1.02	1.07	0.69	1.96	2.05	2.31	0.48	0.93
*AK003679*	*RIKEN:1110014C11*	*0.91*	*1.33*	*1.13*	*1.25*	*0.94*	*1.57*	*1.95*	*2.88*	*0.76*	*0.91*
D87747	CXCR-4	1.07	1.66	1.51	1.29	1.16	1.18	1.58	1.90	0.91	1.15
*NM_011722*	*Dynactin 6*	*1.29*	*1.28*	*1.87*	*1.96*	*1.25*	*3.00*	*2.88*	*4.64*	*0.68*	*0.89*
BC005660	Eukaryotic translation elongation factor 1 alpha 1	0.72	1.36	1.06	0.92	0.88	1.46	2.13	2.27	0.52	0.89
*BG080849*	*CDNA clone H3058D01-5*	*0.78*	*1.55*	*1.92*	*1.62*	*1.01*	*0.70*	*0.74*	*0.94*	*0.62*	*0.80*
AA655703	IMAGE:1149396	0.78	1.49	2.03	2.03	0.90	1.17	1.70	2.42	0.94	1.17
*BE630992*	*IMAGE:3375525*	*1.25*	*0.81*	*2.10*	*2.06*	*1.90*	*1.79*	*1.26*	*1.15*	*0.88*	*0.83*
AK020317	RIKEN 9230106805	1.21	0.74	1.52	1.93	2.93	1.79	1.02	1.84	0.74	0.64
*NM_021099*	*kit oncogene*	*1.32*	*1.02*	*1.09*	*1.23*	*2.12*	*4.71*	*2.06*	*3.61*	*0.60*	*0.53*
BC006720	Karyopherin (importin) alpha 2	0.62	1.42	0.99	0.86	0.57	0.93	1.61	1.55	0.67	1.56
*K02061*	*L32-4A pseudogene*	*0.96*	*1.20*	*1.13*	*1.01*	*1.42*	*1.52*	*1.88*	*3.30*	*0.57*	*0.75*
NM_010686	Laptm5	1.17	0.77	1.14	1.36	2.04	3.88	1.40	0.98	2.34	1.37
*NM_010708*	*Lectin, galactose binding, soluble 9*	*1.08*	*0.73*	*0.80*	*0.81*	*1.49*	*2.67*	*1.56*	*3.06*	*1.20*	*0.85*
NM_020573	Oxysterol binding proteinlike 1A	0.88	1.10	1.10	1.14	1.21	1.71	1.98	2.14	0.99	1.09
*BC005779*	*RIKEN cDNA 0610010E03 gene*	*0.75*	*1.21*	*1.20*	*0.93*	*0.87*	*1.16*	*1.67*	*1.93*	*0.57*	*0.91*
AK002923	RIKEN cDNA 0610043A03 gene	0.97	1.10	1.45	1.21	1.74	2.04	1.61	2.92	0.55	0.78
*AK004571*	*RIKEN cDNA 1200003I10 gene*	*0.82*	*1.47*	*1.65*	*1.65*	*0.57*	*1.02*	*2.15*	*2.11*	*0.71*	*1.38*
NM_023270	RIKEN cDNA 1300002C13 gene	1.36	1.04	1.15	1.42	1.22	1.27	1.57	2.30	0.96	0.67
*AK010014*	*RIKEN cDNA 2310061N23 gene*	*0.87*	*1.44*	*2.15*	*2.27*	*2.16*	*1.00*	*1.15*	*1.49*	*0.70*	*0.78*
NM_011291	Similar to ribosomal protein L7	0.93	1.10	1.18	1.12	1.19	1.67	1.61	3.17	1.09	0.97
*NM_016959*	*Ribosomal protein S3a (Rps3a)*	*1.41*	*0.68*	*1.03*	*1.12*	*1.54*	*1.74*	*1.35*	*3.15*	*1.05*	*0.45*
NM_009096	Ribosomal protein S6 (Rps6)	1.50	0.74	1.08	1.01	1.56	1.68	1.37	4.36	1.05	0.46
*NM_011300*	*Similar to ribosomal protein S7*	*0.94*	*1.22*	*1.03*	*1.03*	*1.00*	*1.13*	*1.55*	*2.50*	*0.78*	*0.95*
NM_023380	Samsn1	1.18	0.84	1.15	1.46	1.58	1.61	1.57	3.02	0.64	0.59
*NM_026506*	*Small nuclear ribonucleoprotein polypeptide G*	*0.65*	*1.31*	*1.21*	*0.81*	*0.75*	*1.37*	*1.87*	*2.49*	*0.37*	*0.57*
D13695	ST2L protein	0.72	1.51	1.69	2.05	0.78	1.08	1.92	1.04	0.58	1.19
*AA199458*	*UDP-glucose ceramide glucosyltransferase*	*0.91*	*1.61*	*1.63*	*2.23*	*0.87*	*1.01*	*3.00*	*3.03*	*0.65*	*1.01*
Dex repressed
*AK010947*	*RIKEN clone 2510009J19*	*1.37*	*0.57*	*0.89*	*0.69*	*0.99*	*0.42*	*0.50*	*0.64*	*2.32*	*1.30*
BC005803	IMAGE:3154023	1.14	0.78	0.84	0.84	1.76	1.46	0.57	0.52	1.25	1.08
*BC006617*	*IMAGE:3967600*	*1.48*	*0.92*	*1.20*	*1.01*	*1.30*	*0.72*	*0.57*	*0.51*	*0.88*	*0.63*
AF290209	Podocalyxin	1.12	1.81	0.57	0.54	1.13	1.24	1.60	1.90	9.41	7.04
*NM_030680*	*Regulator of nonsense transcripts 1*	*1.22*	*1.04*	*0.89*	*0.75*	*0.86*	*0.41*	*0.49*	*0.60*	*1.87*	*1.44*
AK003374	RIKEN clone 1110003L06	1.13	0.89	0.86	0.77	0.84	0.48	0.54	0.64	1.63	1.59
*AK010608*	*RIKEN clone:2410029N08*	*1.46*	*0.87*	*1.30*	*0.91*	*1.43*	*0.41*	*0.58*	*0.46*	*1.48*	*1.06*
NM_011403	Solute carrier family 4 (anion exchanger), Slc4a1	1.32	0.93	0.65	1.05	0.83	0.49	0.61	0.48	2.02	1.28
*NM_031878*	*Smarcd2*	*1.67*	*0.72*	*0.92*	*0.77*	*1.04*	*0.52*	*0.53*	*0.64*	*2.35*	*1.25*
U69135	UCP2	0.71	1.49	1.03	0.80	1.33	1.37	0.58	0.26	1.67	2.46

The ratio between Epo/SCF/Dex over Epo/SCF/ZK at any time point is given as fold change of the duplicate experiments. First indicates first hybridization; second, second hybridization.

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