Table 5. Cooperative signaling among... | American Society of Hematology

Table 5.

Cooperative signaling among Dex, Epo, and SCF: existence of multiple profile groups

Profile Group	Dex	ESD/ESZK	Dex (± Epo, SCF)	Epo	SCF	No. genes
1A	—	—	—	Up	—	54
1B	—	—	—	Down	—	36
2A	—	—	—	—	Up	63
2B	—	—	—	—	Down	58
3A	Up	—	Up	—	—	21
3A′	Up	Up	Up	—	—	18
*3A″*	—	Up	Up	—	—	*106*
3B	Down	—	Down	—	—	33
*3B′*	*Down*	*Down*	*Down*	—	—	2
3B″	—	Down	Down	—	—	72
*4A1*	—	—	—	Up	Up	51
4B1	—	—	—	Down	Down	16
*5A1*	NS	NS	Up	Up	—	5
5A2	NS	NS	Up	Down	—	2
*5B1*	NS	NS	*Down*	Up	—	3
6A1	NS	NS	Up	—	Up	3
*6A2*	NS	NS	Up	—	*Down*	4
6B1	NS	NS	Down	—	Up	1
*7A1*	NS	NS	Up	Up	Up	3
7A3	NS	NS	Up	Down	Down	5
*7B1*	NS	NS	*Down*	Up	Up	3

Profile Group	Dex	ESD/ESZK	Dex (± Epo, SCF)	Epo	SCF	No. genes
1A	—	—	—	Up	—	54
1B	—	—	—	Down	—	36
2A	—	—	—	—	Up	63
2B	—	—	—	—	Down	58
3A	Up	—	Up	—	—	21
3A′	Up	Up	Up	—	—	18
*3A″*	—	Up	Up	—	—	*106*
3B	Down	—	Down	—	—	33
*3B′*	*Down*	*Down*	*Down*	—	—	2
3B″	—	Down	Down	—	—	72
*4A1*	—	—	—	Up	Up	51
4B1	—	—	—	Down	Down	16
*5A1*	NS	NS	Up	Up	—	5
5A2	NS	NS	Up	Down	—	2
*5B1*	NS	NS	*Down*	Up	—	3
6A1	NS	NS	Up	—	Up	3
*6A2*	NS	NS	Up	—	*Down*	4
6B1	NS	NS	Down	—	Up	1
*7A1*	NS	NS	Up	Up	Up	3
7A3	NS	NS	Up	Down	Down	5
*7B1*	NS	NS	*Down*	Up	Up	3

— indicates no regulation; NS, not specified.