Percent c-Myc RNA decrease 24 hours after induction of C/EBPα
C/EBPα construct . | % c-Myc decrease . |
|---|---|
| 42 kDa, wild-type | 94 |
| 30 kDa | 4 |
| Δ126-200 | 42 |
| Δ200-256 | 83 |
| BRM2 | 0 |
| vector | 0 |
| 42 kDa, wild-type | 84 |
| Δ1-70 | 79 |
| BRM3 | 70 |
C/EBPα construct . | % c-Myc decrease . |
|---|---|
| 42 kDa, wild-type | 94 |
| 30 kDa | 4 |
| Δ126-200 | 42 |
| Δ200-256 | 83 |
| BRM2 | 0 |
| vector | 0 |
| 42 kDa, wild-type | 84 |
| Δ1-70 | 79 |
| BRM3 | 70 |
c-Myc RNA was quantitated using Phosphorimager software (Molecular Dynamics, Sunnyvale, CA). The results are presented as percent decrease in c-Myc RNA at 48 hours compared with 0 hours of 1 μM β-estradiol treatment for each stable K562 line as shown in Figure 5. The data in the first 6 lines were derived from Figure 5A and those in the last 3 lines from a completely independent experiment as shown in Figure 5B.