Differential expression of chemokine and chemokine receptor genes in UCB versus AB CD4+ T cells
Gene symbol . | Accession no. . | Gene name . | 0 h . | 6 h . | 16 h . |
|---|---|---|---|---|---|
| Chemokine ligands | |||||
| CCL2 (MCP-1) | S69738 | Chemokine (C-C motif) ligand 2 | — | −9.19* | — |
| CCL3 (MIP-1α) | NM_002983 | Chemokine (C-C motif) ligand 3 | — | −4.59* | −4.00* |
| CCL4 (MIP-1β) | NM_002984 | Chemokine (C-C motif) ligand 4 | −4.00* | −8.57* | −8.00* |
| CCL5 (RANTES) | M21121 | Chemokine (C-C motif) ligand 5 | −22.63* | −18.38* | −5.28* |
| CCL5 (RANTES) | NM_002985 | Chemokine (C-C motif) ligand 5 | −13.93* | −9.19* | −6.06* |
| CCL17 (TARC) | NM_002987 | Chemokine (C-C motif) ligand 17 | — | −2.46* | — |
| CCL20 (MIP-3α) | NM_004591 | Chemokine (C-C motif) ligand 20 | — | −3.03* | −8.00* |
| CXCL2 (GRO-β) | M57731 | Chemokine (C-X-C motif) ligand 2 | — | — | −4.00* |
| CXCL5 (ENA-78) | AK026546 | Chemokine (C-X-C motif) ligand 5 | — | — | −3.48* |
| CXCL9 (MIG) | NM002416 | Chemokine (C-X-C motif) ligand 9 | — | −3.48* | |
| CXCL11 (I-TAC) | AF030514 | Chemokine (C-X-C motif) ligand 11 | — | −3.73* | 2.30 |
| CXCL11 (I-TAC) | AF002985 | Chemokine (C-X-C motif) ligand 11 | — | −3.48* | |
| CXCL13 (BLC/BCA-1) | NM_006419 | Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) | — | — | −19.70* |
| XCL1 | U23772 | Chemokine (C motif) ligand 1 | — | −8.00* | — |
| XCL1 | NM_002995 | Chemokine (C motif) ligand 1 | — | −4.00* | — |
| XCL2 (SCM-1β) | NM_003175 | Chemokine (C motif) ligand 2 | — | −8.00* | — |
| Chemokine receptors | |||||
| CCR1 | AI421071 | Chemokine (C-C motif) receptor 1 | — | — | −6.06* |
| CCR1 | NM_001295 | Chemokine (C-C motif) receptor 1 | — | — | −19.70* |
| CCR2 | NM_000647 | Chemokine (C-C motif) receptor 2 | −6.06* | −7.46* | −9.85* |
| CCR2 | NM_000648 | Chemokine (C-C motif) receptor 2 | −5.28* | −2.64* | −29.86* |
| CCR5 | NM_000579 | Chemokine (C-C motif) receptor 5 | −2.64* | −8.57* | −18.38* |
| CCR6 | NM_004367 | Chemokine (C-C motif) receptor 6 | −10.56* | −8.57* | −8.57* |
| CX3CR1 | U20350 | Chemokine (C-X3-C motif) receptor 1 | −4.00* | — | — |
| CXCR3 | NM_001504 | Chemokine (C-X-C motif) receptor 3 | −2.00* | −2.14* | — |
| CXCR4 | L01639 | Chemokine (C-X-C motif) receptor 4 | — | −2.14* | −2.14* |
| CXCR4 | AF348491 | Chemokine (C-X-C motif) receptor 4 | — | −2.30* | — |
| CXCR6 | NM_006564 | Chemokine (C-X-C motif) receptor 6 | — | −3.03* | −5.66* |
| CXCR6 | U73531 | Chemokine (C-X-C motif) receptor 6 | — | −12.13* | −6.96* |
Gene symbol . | Accession no. . | Gene name . | 0 h . | 6 h . | 16 h . |
|---|---|---|---|---|---|
| Chemokine ligands | |||||
| CCL2 (MCP-1) | S69738 | Chemokine (C-C motif) ligand 2 | — | −9.19* | — |
| CCL3 (MIP-1α) | NM_002983 | Chemokine (C-C motif) ligand 3 | — | −4.59* | −4.00* |
| CCL4 (MIP-1β) | NM_002984 | Chemokine (C-C motif) ligand 4 | −4.00* | −8.57* | −8.00* |
| CCL5 (RANTES) | M21121 | Chemokine (C-C motif) ligand 5 | −22.63* | −18.38* | −5.28* |
| CCL5 (RANTES) | NM_002985 | Chemokine (C-C motif) ligand 5 | −13.93* | −9.19* | −6.06* |
| CCL17 (TARC) | NM_002987 | Chemokine (C-C motif) ligand 17 | — | −2.46* | — |
| CCL20 (MIP-3α) | NM_004591 | Chemokine (C-C motif) ligand 20 | — | −3.03* | −8.00* |
| CXCL2 (GRO-β) | M57731 | Chemokine (C-X-C motif) ligand 2 | — | — | −4.00* |
| CXCL5 (ENA-78) | AK026546 | Chemokine (C-X-C motif) ligand 5 | — | — | −3.48* |
| CXCL9 (MIG) | NM002416 | Chemokine (C-X-C motif) ligand 9 | — | −3.48* | |
| CXCL11 (I-TAC) | AF030514 | Chemokine (C-X-C motif) ligand 11 | — | −3.73* | 2.30 |
| CXCL11 (I-TAC) | AF002985 | Chemokine (C-X-C motif) ligand 11 | — | −3.48* | |
| CXCL13 (BLC/BCA-1) | NM_006419 | Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant) | — | — | −19.70* |
| XCL1 | U23772 | Chemokine (C motif) ligand 1 | — | −8.00* | — |
| XCL1 | NM_002995 | Chemokine (C motif) ligand 1 | — | −4.00* | — |
| XCL2 (SCM-1β) | NM_003175 | Chemokine (C motif) ligand 2 | — | −8.00* | — |
| Chemokine receptors | |||||
| CCR1 | AI421071 | Chemokine (C-C motif) receptor 1 | — | — | −6.06* |
| CCR1 | NM_001295 | Chemokine (C-C motif) receptor 1 | — | — | −19.70* |
| CCR2 | NM_000647 | Chemokine (C-C motif) receptor 2 | −6.06* | −7.46* | −9.85* |
| CCR2 | NM_000648 | Chemokine (C-C motif) receptor 2 | −5.28* | −2.64* | −29.86* |
| CCR5 | NM_000579 | Chemokine (C-C motif) receptor 5 | −2.64* | −8.57* | −18.38* |
| CCR6 | NM_004367 | Chemokine (C-C motif) receptor 6 | −10.56* | −8.57* | −8.57* |
| CX3CR1 | U20350 | Chemokine (C-X3-C motif) receptor 1 | −4.00* | — | — |
| CXCR3 | NM_001504 | Chemokine (C-X-C motif) receptor 3 | −2.00* | −2.14* | — |
| CXCR4 | L01639 | Chemokine (C-X-C motif) receptor 4 | — | −2.14* | −2.14* |
| CXCR4 | AF348491 | Chemokine (C-X-C motif) receptor 4 | — | −2.30* | — |
| CXCR6 | NM_006564 | Chemokine (C-X-C motif) receptor 6 | — | −3.03* | −5.66* |
| CXCR6 | U73531 | Chemokine (C-X-C motif) receptor 6 | — | −12.13* | −6.96* |
Criteria for inclusion were as follows: at least one present (P) call and FC ≥ 2 and change call ≠ no change (NC). A positive number indicates higher expression in UCB than AB; a negative number (*), lower expression in UCB than AB; —, the gene did not meet inclusion criteria at that time point; and genes with multiple results indicate multiple probe sets for that gene on the microarray.