Table 1.

Genes differentially expressed in N, MGUS, and MM





Fold change
Gene
Name
Accession no.
N vs MGUS
N vs MM
FABP4  Fatty acid binding protein 4, adipocyte   AA128249   −12.2   −13.94  
PPBP  Pro-platelet basic protein (chemokine [C-X-C motif] ligand 7)   M54995   NA   −12.00  
CD5L  CD5 antigen-like (scavenger receptor cysteine rich family)   U82812   −10.49   −11.2  
CD163  CD 163 antigen   Z22971   −6.51   −7.81  
HLA-DRA  Major histocompatibility complex, class 2, DR α   J00194   −6.18   −9.42  
SEPP1  Selenoprotein P, plasma, 1   Z11793   −5.89   −9.29  
FNBP1  Formin-binding protein 1   AB011126   −5.5   −8.48  
SAT  Spermidine/spermine N1-acetyltransferase   M77693   −4.8   −11.24  
Cluster Incl*  Unknown   AA203487   −4.61   −6.91  
CTSH  Cathepsin H   X16832   −4.57   −9.52  
PF4  Platelet factor 4 (chemokine [C-X-C motif] ligand 4)   M25897   −4.15   −15.38  
CLECSF2  C-type (calcium-dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced)   X96719   −4.47   −7.07  
HLA-DPA1  Major histocompatibility complex, class 2, DP α 1   X00457   −3.27   −5.82  
TMSB4X  Thymosin, β4, X chromosome   M17733   −3.04   −7.05  
TNFRSF7  Tumor necrosis factor receptor superfamily, member 7   M63928   −2.96   −7.64  
MARCKS  Myristoylated alanine-rich protein kinase C substrate   D10522   −1.95   −4.71  
RING1  Ring finger protein 1   AL031228   1.4   2.92  
NY-REN-24*  NY-REN-24 antigen   AF052087   NA   2.18  
NME1  Nonmetastatic cells 1, protein (NM23A) expressed in   X73066   2.4   2.18  
GLI3  GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)   M57609   2.41   2.14  
WIT1*  Wilms tumor-associated protein   X69950   2.53   2.42  
RPL14  Ribosomal protein L 14   D87735   NA   2.56  
PPP1CA  Protein phosphatase 1, catalytic subunit, α isoform   S57501   2.53   2.61  
Cluster Incl*  Unknown   A1687419   NA   2.71  
GNL1
 
Guanine nucleotide binding protein-like 1
 
L25665
 
4.36
 
2.85
 




Fold change
Gene
Name
Accession no.
N vs MGUS
N vs MM
FABP4  Fatty acid binding protein 4, adipocyte   AA128249   −12.2   −13.94  
PPBP  Pro-platelet basic protein (chemokine [C-X-C motif] ligand 7)   M54995   NA   −12.00  
CD5L  CD5 antigen-like (scavenger receptor cysteine rich family)   U82812   −10.49   −11.2  
CD163  CD 163 antigen   Z22971   −6.51   −7.81  
HLA-DRA  Major histocompatibility complex, class 2, DR α   J00194   −6.18   −9.42  
SEPP1  Selenoprotein P, plasma, 1   Z11793   −5.89   −9.29  
FNBP1  Formin-binding protein 1   AB011126   −5.5   −8.48  
SAT  Spermidine/spermine N1-acetyltransferase   M77693   −4.8   −11.24  
Cluster Incl*  Unknown   AA203487   −4.61   −6.91  
CTSH  Cathepsin H   X16832   −4.57   −9.52  
PF4  Platelet factor 4 (chemokine [C-X-C motif] ligand 4)   M25897   −4.15   −15.38  
CLECSF2  C-type (calcium-dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced)   X96719   −4.47   −7.07  
HLA-DPA1  Major histocompatibility complex, class 2, DP α 1   X00457   −3.27   −5.82  
TMSB4X  Thymosin, β4, X chromosome   M17733   −3.04   −7.05  
TNFRSF7  Tumor necrosis factor receptor superfamily, member 7   M63928   −2.96   −7.64  
MARCKS  Myristoylated alanine-rich protein kinase C substrate   D10522   −1.95   −4.71  
RING1  Ring finger protein 1   AL031228   1.4   2.92  
NY-REN-24*  NY-REN-24 antigen   AF052087   NA   2.18  
NME1  Nonmetastatic cells 1, protein (NM23A) expressed in   X73066   2.4   2.18  
GLI3  GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome)   M57609   2.41   2.14  
WIT1*  Wilms tumor-associated protein   X69950   2.53   2.42  
RPL14  Ribosomal protein L 14   D87735   NA   2.56  
PPP1CA  Protein phosphatase 1, catalytic subunit, α isoform   S57501   2.53   2.61  
Cluster Incl*  Unknown   A1687419   NA   2.71  
GNL1
 
Guanine nucleotide binding protein-like 1
 
L25665
 
4.36
 
2.85
 

Values in -fold change are expressed using the N PC group as the baseline. NA indicates not applicable.

*

Not a human gene nomenclature database symbol.

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