Summary of CTL epitopes derived from CMV-pp65
Newly identified epitopes . | . | . | . | Previously reported epitopes . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HLA . | Position, aa . | Sequence . | Length . | HLA . | Position, aa . | Sequence . | Length . | Reference . | |||||||
| A*0207 | 522-530 | RIFAELEGV | 9 | A*0101 | 363-373 | YSEHPTFTSQY | 12 | 29,30 | |||||||
| A*1101 | 501-509 | ATVQGQNLK | 9 | A2 | 14-22 | VLGPISGHV | 10 | 31 | |||||||
| B*1501 | 215-223 | KMQVIGDQY | 9 | A2 | 120-138 | MLNIPSINV | 9 | 31 | |||||||
| B*4001 | 232-240 | CEDVPSGKL | 9 | A2 | 495-503 | NLVPMVATV | 9 | 14,32 | |||||||
| B*4001 | 267-275 | HERNGFTVL† | 9 | A*1101 | 16-24 | GPISGHVLK | 9 | 9,30 | |||||||
| B*4002 | 267-275 | HERNGFTVL† | 9 | A*2402 | 341-349 | QYDPVAALF‡ | 9 | 15 | |||||||
| B*4006 | 525-534 | AELEGVWQPA | 10 | A*2402 | 369-379 | FTSQYRIQGKL | 11 | 9,30 | |||||||
| B*4403 | 364-373 | SEHPTFTSQY | 10 | A*2402 | 113-121 | VYALPLKML | 9 | 33 | |||||||
| B*5101 | 545-552 | DALPGPCI | 8 | A*6801/2 | 186-196 | FVFPTKDVALR | 11 | 30 | |||||||
| Cw*0102 | 7-15 | RCPEMISVL | 9 | B7 | 265-274 | RPHERNGFTV | 10 | 14,34 | |||||||
| Cw*0401 | 341-349 | QYDPVAALF‡ | 9 | B7 | 417-426 | TPRVTGGGAM | 10 | 14,34 | |||||||
| Cw*0801 | 198-206 | VVCAHELVC§ | 9 | B35(B*3501) | 123-131 | IPSINVHHY | 9 | 26 | |||||||
| Cw*1202 | 294-302 | VAFTSHEHF | 9 | B35(B*3502) | 188-195 | FPTKDVAL | 8 | 9,14,30 | |||||||
| Cw*1502 | 198-206 | VVCAHELVC§ | 9 | B35(B*3503) | 187-195 | VFPTKDVAL | 9 | 14,35 | |||||||
| B*3801/2 | 367-379 | PTFTSQYRIQGKL | 13 | 14,34 | |||||||||||
| B44(B*4402) | 512-521 | EFFWDANDIY | 10 | 14,34,35 | |||||||||||
| B*5201 | 155-163 | QMWQARLTV | 9 | 27 | |||||||||||
Newly identified epitopes . | . | . | . | Previously reported epitopes . | . | . | . | . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HLA . | Position, aa . | Sequence . | Length . | HLA . | Position, aa . | Sequence . | Length . | Reference . | |||||||
| A*0207 | 522-530 | RIFAELEGV | 9 | A*0101 | 363-373 | YSEHPTFTSQY | 12 | 29,30 | |||||||
| A*1101 | 501-509 | ATVQGQNLK | 9 | A2 | 14-22 | VLGPISGHV | 10 | 31 | |||||||
| B*1501 | 215-223 | KMQVIGDQY | 9 | A2 | 120-138 | MLNIPSINV | 9 | 31 | |||||||
| B*4001 | 232-240 | CEDVPSGKL | 9 | A2 | 495-503 | NLVPMVATV | 9 | 14,32 | |||||||
| B*4001 | 267-275 | HERNGFTVL† | 9 | A*1101 | 16-24 | GPISGHVLK | 9 | 9,30 | |||||||
| B*4002 | 267-275 | HERNGFTVL† | 9 | A*2402 | 341-349 | QYDPVAALF‡ | 9 | 15 | |||||||
| B*4006 | 525-534 | AELEGVWQPA | 10 | A*2402 | 369-379 | FTSQYRIQGKL | 11 | 9,30 | |||||||
| B*4403 | 364-373 | SEHPTFTSQY | 10 | A*2402 | 113-121 | VYALPLKML | 9 | 33 | |||||||
| B*5101 | 545-552 | DALPGPCI | 8 | A*6801/2 | 186-196 | FVFPTKDVALR | 11 | 30 | |||||||
| Cw*0102 | 7-15 | RCPEMISVL | 9 | B7 | 265-274 | RPHERNGFTV | 10 | 14,34 | |||||||
| Cw*0401 | 341-349 | QYDPVAALF‡ | 9 | B7 | 417-426 | TPRVTGGGAM | 10 | 14,34 | |||||||
| Cw*0801 | 198-206 | VVCAHELVC§ | 9 | B35(B*3501) | 123-131 | IPSINVHHY | 9 | 26 | |||||||
| Cw*1202 | 294-302 | VAFTSHEHF | 9 | B35(B*3502) | 188-195 | FPTKDVAL | 8 | 9,14,30 | |||||||
| Cw*1502 | 198-206 | VVCAHELVC§ | 9 | B35(B*3503) | 187-195 | VFPTKDVAL | 9 | 14,35 | |||||||
| B*3801/2 | 367-379 | PTFTSQYRIQGKL | 13 | 14,34 | |||||||||||
| B44(B*4402) | 512-521 | EFFWDANDIY | 10 | 14,34,35 | |||||||||||
| B*5201 | 155-163 | QMWQARLTV | 9 | 27 | |||||||||||
Same peptide found to be presented by different alleles or subtypes of HLA.