Table 2.

Univariate analysis to predict number of collected CD34 cells equaling or exceeding 2 × 106/kg after first mobilization


Variables

Results

P
Age, y   53.5 (38-66)   .73  
Male-female ratio   33/5   .57  
Initial Binet (B/C) stage before FDR-CY   34/4   .51  
Blood count at presentation before FDR-CY   
    Hemoglobin, g/L   135.0 (100.0-170.0)   .17  
    Lymphocytes, × 109/L   45.5 (5.0-286.0)   .99  
    Neutrophils, × 109/L   4.3 (0.0-21.0)   .77  
    Platelets, × 109/L   183.5 (57.0-279.0)   .42  
No. FuCy courses (c)*  6c (n = 34); 5c (n = 2); 4c (n = 1); 2c (n = 1)   .51  
Disease status at evaluation after FDR-CY: PR/CR   12/26   .63  
Blood count at evaluation, 2 mo after last FDR-CY c*   
    Hemoglobin, g/L   137.5 (73.0-156.0)   .64  
    Lymphocytes, × 109/L   0.7 (0.1-1.7)   .30  
    Neutrophils, × 109/L   2.9 (0.9-8.0)   .11  
    Platelets, × 109/L   178.0 (50.0-330.0)   .052  
Interval from last FDR-CY c to mobilization, d   178.0 (69-377)   .19  
Mobilization: filgrastim/lenograstim   25/13   .67  
Blood count immediately before mobilization*   
    Hemoglobin, g/L   142.0 (95.0-163.0)   .56  
    Leukocytes, × 109/L   4.3 (2.1-11.4)   .097  
    Neutrophils, × 109/L   2.8 (1.1-8.7)   .085  
    Lymphocytes, × 109/L   0.8 (0.2-5.4)   .96  
    Monocytes, × 109/L   0.3 (0.1-0.8)   .20  
    Platelets, × 109/L
 
177.5 (86.0-461.0)
 
.009
 

Variables

Results

P
Age, y   53.5 (38-66)   .73  
Male-female ratio   33/5   .57  
Initial Binet (B/C) stage before FDR-CY   34/4   .51  
Blood count at presentation before FDR-CY   
    Hemoglobin, g/L   135.0 (100.0-170.0)   .17  
    Lymphocytes, × 109/L   45.5 (5.0-286.0)   .99  
    Neutrophils, × 109/L   4.3 (0.0-21.0)   .77  
    Platelets, × 109/L   183.5 (57.0-279.0)   .42  
No. FuCy courses (c)*  6c (n = 34); 5c (n = 2); 4c (n = 1); 2c (n = 1)   .51  
Disease status at evaluation after FDR-CY: PR/CR   12/26   .63  
Blood count at evaluation, 2 mo after last FDR-CY c*   
    Hemoglobin, g/L   137.5 (73.0-156.0)   .64  
    Lymphocytes, × 109/L   0.7 (0.1-1.7)   .30  
    Neutrophils, × 109/L   2.9 (0.9-8.0)   .11  
    Platelets, × 109/L   178.0 (50.0-330.0)   .052  
Interval from last FDR-CY c to mobilization, d   178.0 (69-377)   .19  
Mobilization: filgrastim/lenograstim   25/13   .67  
Blood count immediately before mobilization*   
    Hemoglobin, g/L   142.0 (95.0-163.0)   .56  
    Leukocytes, × 109/L   4.3 (2.1-11.4)   .097  
    Neutrophils, × 109/L   2.8 (1.1-8.7)   .085  
    Lymphocytes, × 109/L   0.8 (0.2-5.4)   .96  
    Monocytes, × 109/L   0.3 (0.1-0.8)   .20  
    Platelets, × 109/L
 
177.5 (86.0-461.0)
 
.009
 

Variables were demographic, clinical, and biologic characteristics of 38 B-CLL patients. All numbers in parentheses are ranges, and all numbers preceding them are medians.

*

Continuous variables.

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