Induction and salvage chemotherapy regimens
Regimen . | Dose and route . | Day . | Frequency . |
|---|---|---|---|
| CHOP | |||
| C - cyclophosphamide | 750 mg/m2 IV | 1 | Repeat every 21 d |
| H - doxorubicin (Adriamycin) | 50 mg/m2 IV | 1 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1 | |
| P - prednisolone | 100 mg PO | 1-5 | |
| m-BACOD | |||
| m - methotrexate (+ leucovorin) | 200 mg/m2 IV | 8, 15 | Repeat every 21 d |
| B - bleomycin | 4 mg/m2 IV | 1 | |
| A - doxorubicin (Adriamycin) | 45 mg/m2 IV | 1 | |
| C - cyclophosphamide | 600 mg/m2 IV | 1 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1 | |
| D - dexamethasone (Decadron) | 6 mg/m2 PO | 1-5 | |
| ProMACE-CytaBOM | |||
| Pro - prednisolone | 60 mg/m2 PO | 1-14 | Repeat every 21 d |
| A - doxorubicin (Adriamycin) | 25 mg/m2 IV | 1 | |
| C - cyclophosphamide | 650 mg/m2 IV | 1 | |
| E - etoposide | 120 mg/m2 IV | 1 | |
| Cyta - cytarabine | 300 mg/m2 IV | 8 | |
| B - bleomycin | 5 mg/m2 IV | 8 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 8 | |
| M - methotrexate (+ leucovorin) | 120 mg/m2 IV | 8 | |
| COPP | |||
| C - cyclophosphamide | 450 mg/m2 IV | 1, 8 | Repeat every 28 d |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1, 8 | |
| P - procarbazine | 100 mg/m2 PO | 1-14 | |
| P - prednisolone | 40 mg/m2 PO | 1-14 | |
| IMVP-16 | |||
| I-ifosfamide | 1 gm/m2 IV | 1-5 | |
| M-methotrexate | 30 mg/m2 IM | 3, 10 | |
| VP-16 | 100 mg/m2 IV | 1-3 | |
| DHAP | |||
| Cisplatin | 100 mg/m2 IV | 1 | |
| Ara-C | 4 g/m2 IV | 1-2 | |
| Dexamethasone | 40 mg IV | 1-4 |
Regimen . | Dose and route . | Day . | Frequency . |
|---|---|---|---|
| CHOP | |||
| C - cyclophosphamide | 750 mg/m2 IV | 1 | Repeat every 21 d |
| H - doxorubicin (Adriamycin) | 50 mg/m2 IV | 1 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1 | |
| P - prednisolone | 100 mg PO | 1-5 | |
| m-BACOD | |||
| m - methotrexate (+ leucovorin) | 200 mg/m2 IV | 8, 15 | Repeat every 21 d |
| B - bleomycin | 4 mg/m2 IV | 1 | |
| A - doxorubicin (Adriamycin) | 45 mg/m2 IV | 1 | |
| C - cyclophosphamide | 600 mg/m2 IV | 1 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1 | |
| D - dexamethasone (Decadron) | 6 mg/m2 PO | 1-5 | |
| ProMACE-CytaBOM | |||
| Pro - prednisolone | 60 mg/m2 PO | 1-14 | Repeat every 21 d |
| A - doxorubicin (Adriamycin) | 25 mg/m2 IV | 1 | |
| C - cyclophosphamide | 650 mg/m2 IV | 1 | |
| E - etoposide | 120 mg/m2 IV | 1 | |
| Cyta - cytarabine | 300 mg/m2 IV | 8 | |
| B - bleomycin | 5 mg/m2 IV | 8 | |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 8 | |
| M - methotrexate (+ leucovorin) | 120 mg/m2 IV | 8 | |
| COPP | |||
| C - cyclophosphamide | 450 mg/m2 IV | 1, 8 | Repeat every 28 d |
| O - vincristine (Oncovin) | 1.4 mg/m2 IV | 1, 8 | |
| P - procarbazine | 100 mg/m2 PO | 1-14 | |
| P - prednisolone | 40 mg/m2 PO | 1-14 | |
| IMVP-16 | |||
| I-ifosfamide | 1 gm/m2 IV | 1-5 | |
| M-methotrexate | 30 mg/m2 IM | 3, 10 | |
| VP-16 | 100 mg/m2 IV | 1-3 | |
| DHAP | |||
| Cisplatin | 100 mg/m2 IV | 1 | |
| Ara-C | 4 g/m2 IV | 1-2 | |
| Dexamethasone | 40 mg IV | 1-4 |
IV indicates intravenously, PO, orally, IM, intramuscularly.