Treatment and outcome of 66 patients with primary RT or primary chemotherapy*
Initial treatment, salvage therapy, and outcome . | n . |
---|---|
RT | 7 |
Median age | 40 y |
CR | 7 |
NR | 0 |
Relapse | |
Local | 4 |
Systemic | 0 |
Median time from CR to relapse | 187 mo |
Salvage treatment for patients with relapse | |
CR | 2 |
NR | 2 |
Total no. of deaths | 2 |
Anthracycline-containing regimen + RT consolidation | |
CHOP | 25 |
m-BACOD | 17 |
ProMACE-CytaBOM | 5 |
Median age | 42 y |
CR | 31 |
NR | 16 |
Relapse | |
Local | 8 |
Systemic | 5 |
Median time from CR to relapse | 100 mo |
Salvage treatment for relapsed patients | |
CR | 3 |
PR | 1 |
NR | 9 |
Total no. of deaths | 23 |
Nonanthracycline-containing regimen + RT consolidation | |
COPP | 12 |
Median age | 72 y |
CR | 4 |
NR | 8 |
Relapse | |
Local | 1 |
Systemic | 0 |
Median time from CR to relapse | 4 mo |
Salvage treatment for patients with relapse | |
CR | 0 |
NR | 1 |
Total no. of deaths | 9 |
Initial treatment, salvage therapy, and outcome . | n . |
---|---|
RT | 7 |
Median age | 40 y |
CR | 7 |
NR | 0 |
Relapse | |
Local | 4 |
Systemic | 0 |
Median time from CR to relapse | 187 mo |
Salvage treatment for patients with relapse | |
CR | 2 |
NR | 2 |
Total no. of deaths | 2 |
Anthracycline-containing regimen + RT consolidation | |
CHOP | 25 |
m-BACOD | 17 |
ProMACE-CytaBOM | 5 |
Median age | 42 y |
CR | 31 |
NR | 16 |
Relapse | |
Local | 8 |
Systemic | 5 |
Median time from CR to relapse | 100 mo |
Salvage treatment for relapsed patients | |
CR | 3 |
PR | 1 |
NR | 9 |
Total no. of deaths | 23 |
Nonanthracycline-containing regimen + RT consolidation | |
COPP | 12 |
Median age | 72 y |
CR | 4 |
NR | 8 |
Relapse | |
Local | 1 |
Systemic | 0 |
Median time from CR to relapse | 4 mo |
Salvage treatment for patients with relapse | |
CR | 0 |
NR | 1 |
Total no. of deaths | 9 |
CR indicates complete remission; PR, partial remission (> 50% reduction in tumor mass); NR, nonremission. The chemotherapy regimens are explained in Table 1.
Excluding one patient who achieved CR after initial treatment with surgery alone.