Table 3. Phenotypic parameters for... | American Society of Hematology

Table 3.

Phenotypic parameters for Tyr/Tyr1584 and Tyr/Cys1584 individuals

ID	Position 1584	Blood group	VWF:Ag, %	VWF:RCo, %	RCo/Ag ratio	VWF:CB, %	CBA/Ag ratio	FVIII:C, %
C1	Tyr/Tyr	A	99	145	1.47	79	0.80	88
C2	Tyr/Tyr	O	72	123	1.71	57	0.79	86
C3	Tyr/Tyr	A	94	133	1.41	76	0.81	97
2:3	Tyr/Cys	O	86	53	0.62	80	0.93	76
C154	Tyr/Cys	O	34	—	—	18	0.53	40
C188	Tyr/Cys	A	309^*	464	1.50	262	0.84	192
M^*	Tyr/Cys	O	13	< 10	> 0.76	—	—	37
			16	18	1.13	12	0.75	48
			13	< 10	> 0.77	—	—	27
			21	13	0.61	9	0.42	48

ID	Position 1584	Blood group	VWF:Ag, %	VWF:RCo, %	RCo/Ag ratio	VWF:CB, %	CBA/Ag ratio	FVIII:C, %
C1	Tyr/Tyr	A	99	145	1.47	79	0.80	88
C2	Tyr/Tyr	O	72	123	1.71	57	0.79	86
C3	Tyr/Tyr	A	94	133	1.41	76	0.81	97
2:3	Tyr/Cys	O	86	53	0.62	80	0.93	76
C154	Tyr/Cys	O	34	—	—	18	0.53	40
C188	Tyr/Cys	A	309^*	464	1.50	262	0.84	192
M^*	Tyr/Cys	O	13	< 10	> 0.76	—	—	37
			16	18	1.13	12	0.75	48
			13	< 10	> 0.77	—	—	27
			21	13	0.61	9	0.42	48

C1-3 indicate individuals from a cohort of 200 random subjects; M indicates patient M; 2:3 indicates the sister of patient M; C154 and C188 indicate the 2 Tyr/Cys 1584 heterozygous individuals from the cohort of 200 random subjects;—indicates not determined.

Data are shown for testing on 4 independent occasions.

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