Table 3.

Response to clofarabine therapy in pediatric leukemia



No. (%)
Response
AML
ALL
Total
CR   1 (13)   4 (24)   5 (20)  
PR   2 (25)   1 (6)   3 (12)  
HI   1 (13)   3 (18)   4 (16)  
Stable disease   1 (13)   3 (18)   4 (16)  
Early death   1 (13)   0 (0)   1 (4)  
Primary resistance   2 (25)   4 (24)   6 (24)  
Secondary resistance
 
0 (0)
 
2 (12)
 
2 (8)
 


No. (%)
Response
AML
ALL
Total
CR   1 (13)   4 (24)   5 (20)  
PR   2 (25)   1 (6)   3 (12)  
HI   1 (13)   3 (18)   4 (16)  
Stable disease   1 (13)   3 (18)   4 (16)  
Early death   1 (13)   0 (0)   1 (4)  
Primary resistance   2 (25)   4 (24)   6 (24)  
Secondary resistance
 
0 (0)
 
2 (12)
 
2 (8)
 

N = 25 patients.

CR indicates complete remission; PR, partial remission, and HI, hematologic improvement.

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