Clinical characteristics of patient population
Patient no. .  | Age, y .  | Major clinical manifestations .  | Prior therapy .  | 
|---|---|---|---|
| 1 | 37 | Mucosal ulcerations, dermatitis anemia, thrombocytopenia, splenomegaly | Prednisone, hydroxyurea, IFN-α, anti-IL-5 antibody (SCH55700) | 
| 2 | 51 | Mucosal ulcerations, dermatitis, splenomegaly | Prednisone, hydroxyurea, IFN-α, anti-IL-5 antibody (SCH55700) | 
| 3 | 47 | Pulmonary fibrosis, dermatitis, splenomegaly | None | 
| 4 | 36 | Splenomegaly | Hydroxyurea | 
| 5 | 47 | Endomyocardial fibrosis, pulmonary fibrosis, dermatitis, splenomegaly | Prednisone, hydroxyurea, IFN-α, cyclosporin A | 
| 6 | 29 | Endomyocardial fibrosis, peripheral neuropathy, splenomegaly | Prednisone, hydroxyurea | 
| 7 | 33 | Endomyocardial fibrosis, hepatosplenomegaly | Imatinib mesylate (100 mg daily) | 
|  8  |  30  |  Myocarditis, sinusitis, obstructive pulmonary disease, splenomegaly  |  Prednisone, hydroxyurea  | 
Patient no. .  | Age, y .  | Major clinical manifestations .  | Prior therapy .  | 
|---|---|---|---|
| 1 | 37 | Mucosal ulcerations, dermatitis anemia, thrombocytopenia, splenomegaly | Prednisone, hydroxyurea, IFN-α, anti-IL-5 antibody (SCH55700) | 
| 2 | 51 | Mucosal ulcerations, dermatitis, splenomegaly | Prednisone, hydroxyurea, IFN-α, anti-IL-5 antibody (SCH55700) | 
| 3 | 47 | Pulmonary fibrosis, dermatitis, splenomegaly | None | 
| 4 | 36 | Splenomegaly | Hydroxyurea | 
| 5 | 47 | Endomyocardial fibrosis, pulmonary fibrosis, dermatitis, splenomegaly | Prednisone, hydroxyurea, IFN-α, cyclosporin A | 
| 6 | 29 | Endomyocardial fibrosis, peripheral neuropathy, splenomegaly | Prednisone, hydroxyurea | 
| 7 | 33 | Endomyocardial fibrosis, hepatosplenomegaly | Imatinib mesylate (100 mg daily) | 
|  8  |  30  |  Myocarditis, sinusitis, obstructive pulmonary disease, splenomegaly  |  Prednisone, hydroxyurea  |