mRNA level of each haplotype in 6 AB and 7 AC heterozygotes evaluated by sequencing of independent cDNA clones
. | . | . | Haplotype A clones† . | . | Haplotype B or C clones† . | . | ||
|---|---|---|---|---|---|---|---|---|
| Subject . | Genotype . | Total clones* . | n . | % . | n . | % . | ||
| 1 | AB | 8 | 0 | 0 | 8 | 100 | ||
| 2 | AB | 10 | 1 | 10 | 9 | 90 | ||
| 3 | AB | 15 | 3 | 20 | 12 | 80 | ||
| 4 | AB | 8 | 3 | 38 | 5 | 63 | ||
| 5 | AB | 8 | 1 | 13 | 7 | 88 | ||
| 6 | AB | 10 | 1 | 10 | 9 | 90 | ||
| 7 | AC | 10 | 2 | 10 | 18 | 90 | ||
| 8 | AC | 15 | 3 | 15 | 17 | 85 | ||
| 9 | AC | 36 | 4 | 36 | 7 | 64 | ||
| 10 | AC | 14 | 1 | 14 | 6 | 86 | ||
| 11 | AC | 20 | 2 | 20 | 8 | 80 | ||
| 12 | AC | 11 | 1 | 11 | 8 | 89 | ||
| 13 | AC | 25 | 2 | 25 | 6 | 75 | ||
| Total | — | 144 | 24 | 17 | 120 | 83 | ||
. | . | . | Haplotype A clones† . | . | Haplotype B or C clones† . | . | ||
|---|---|---|---|---|---|---|---|---|
| Subject . | Genotype . | Total clones* . | n . | % . | n . | % . | ||
| 1 | AB | 8 | 0 | 0 | 8 | 100 | ||
| 2 | AB | 10 | 1 | 10 | 9 | 90 | ||
| 3 | AB | 15 | 3 | 20 | 12 | 80 | ||
| 4 | AB | 8 | 3 | 38 | 5 | 63 | ||
| 5 | AB | 8 | 1 | 13 | 7 | 88 | ||
| 6 | AB | 10 | 1 | 10 | 9 | 90 | ||
| 7 | AC | 10 | 2 | 10 | 18 | 90 | ||
| 8 | AC | 15 | 3 | 15 | 17 | 85 | ||
| 9 | AC | 36 | 4 | 36 | 7 | 64 | ||
| 10 | AC | 14 | 1 | 14 | 6 | 86 | ||
| 11 | AC | 20 | 2 | 20 | 8 | 80 | ||
| 12 | AC | 11 | 1 | 11 | 8 | 89 | ||
| 13 | AC | 25 | 2 | 25 | 6 | 75 | ||
| Total | — | 144 | 24 | 17 | 120 | 83 | ||
Statistical analysis was performed on percentages using the Mann-Whitney U test and the proportions of haplotype A clones were significantly lower than that of haplotype B or C (P < .0001).
— indicates not applicable.
Total number of OPN cDNA clones analyzed in that subject.
Number (n) and percentage (%) of clones with haplotype A and B or C.