Table 3.

F4/80+ cell densities in the tissues of Csf1op/Csf1op; TgCS5/+ mice


Tissues

Age

Wild-type

Csf1op/Csf1op

Csf1op/Csf1op; TgCS5/+
Bladder*  3 mo   184 ± 47   32 ± 16   210 ± 38  
Adrenal*  3 mo   237 ± 19   31 ± 9   171 ± 15  
Salivary gland (sublinguinal)*  3 mo   166 ± 3   86 ± 11   146 ± 49  
Large intestine*  2 wk   304 ± 35   35 ± 10   165 ± 42  
Kidney     
Cortex*  2 wk   217 ± 13   42 ± 9   195 ± 33  
Medullar*  2 wk   299 ± 21   119 ± 42   207 ± 22  
Liver   2 d*  663 ± 82   432 ± 43   638 ± 35  
  3 mo*  336 ± 29   161 ± 30   145 ± 19  
Dermis*
 
2 d
 
412 ± 62
 
184 ± 45
 
310 ± 16
 

Tissues

Age

Wild-type

Csf1op/Csf1op

Csf1op/Csf1op; TgCS5/+
Bladder*  3 mo   184 ± 47   32 ± 16   210 ± 38  
Adrenal*  3 mo   237 ± 19   31 ± 9   171 ± 15  
Salivary gland (sublinguinal)*  3 mo   166 ± 3   86 ± 11   146 ± 49  
Large intestine*  2 wk   304 ± 35   35 ± 10   165 ± 42  
Kidney     
Cortex*  2 wk   217 ± 13   42 ± 9   195 ± 33  
Medullar*  2 wk   299 ± 21   119 ± 42   207 ± 22  
Liver   2 d*  663 ± 82   432 ± 43   638 ± 35  
  3 mo*  336 ± 29   161 ± 30   145 ± 19  
Dermis*
 
2 d
 
412 ± 62
 
184 ± 45
 
310 ± 16
 

Data are from at least 12 low-power fields of tissues from 2 mice of each genotype. Data for dermis are expressed as cells/mm. Mean ± SD.

*

Significant difference between wild-type and Csf1op/Csf1op.

Significant difference between Csf1op/Csf1op and Csf1op/Csf1op; TgCS5/+.

Significant difference between wild-type and Csf1op/Csf1op; TgCS5/+.

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