Table 5. Posterior iliac crest BM... | American Society of Hematology

Table 5.

Posterior iliac crest BM clonogenic activity in CFU per 10⁵ MNCs plated

	Preirradiated	H6	D1	D3/D4	D42	D450
Control monkeys
CFU-GMs	254*	5.3 ± 2.7	9.5 ± 6.4	7 ± 4.7	13.3 ± 3.9	67.3 ± 24
BFU-Es	82*	1.3 ± 0.8	1.8 ± 0.9	3.8 ± 1.7	38.8 ± 21	57 ± 17
CFU-GEMMs	65.5*	0.8 ± 0.3	0.5 ± 0.5	4.8 ± 1.9	22.8 ± 15	20.1 ± 3.3
Cumulated CFUs	402*	7.3 ± 2.1	11.3 ± 6.5	15.5 ± 7.3	74.8 ± 39	144.3 ± 38
4F-treated monkeys
CFU-GMs	93 ± 32.5	11 ± 10.5	6.3 ± 5.2	30.8 ± 26	34.3 ± 11†	103 ± 37
BFU-Es	36 ± 17	0	0.8 ± 0.3	5.5 ± 2.7	85.8 ± 22	110 ± 63
CFU-GEMMs	42 ± 17	0.5 ± 0.5	0.25 ± 0.3	4.5 ± 2.3	67.8 ± 16	30.7 ± 13
Cumulated CFUs	171 ± 54	11.5 ± 11	7.3 ± 4.9	40.8 ± 24	188 ± 43	243 ± 110

	Preirradiated	H6	D1	D3/D4	D42	D450
Control monkeys
CFU-GMs	254*	5.3 ± 2.7	9.5 ± 6.4	7 ± 4.7	13.3 ± 3.9	67.3 ± 24
BFU-Es	82*	1.3 ± 0.8	1.8 ± 0.9	3.8 ± 1.7	38.8 ± 21	57 ± 17
CFU-GEMMs	65.5*	0.8 ± 0.3	0.5 ± 0.5	4.8 ± 1.9	22.8 ± 15	20.1 ± 3.3
Cumulated CFUs	402*	7.3 ± 2.1	11.3 ± 6.5	15.5 ± 7.3	74.8 ± 39	144.3 ± 38
4F-treated monkeys
CFU-GMs	93 ± 32.5	11 ± 10.5	6.3 ± 5.2	30.8 ± 26	34.3 ± 11†	103 ± 37
BFU-Es	36 ± 17	0	0.8 ± 0.3	5.5 ± 2.7	85.8 ± 22	110 ± 63
CFU-GEMMs	42 ± 17	0.5 ± 0.5	0.25 ± 0.3	4.5 ± 2.3	67.8 ± 16	30.7 ± 13
Cumulated CFUs	171 ± 54	11.5 ± 11	7.3 ± 4.9	40.8 ± 24	188 ± 43	243 ± 110

Values presented as mean ± SD. Statistical significance between treated and control groups is expressed. P < .05.

Mean from 2 animals.

Significantly different from the control value.