Table 2.

Invasive fungal infections diagnosed during the study period


Infection

Fluconazole

Itraconazole
Invasive mold infections (%)*  23 (16)   23 (15)  
    Proven   9 (6)   11 (7)  
    Probable   11 (7)   5 (3)  
    Possible   3 (2)   7 (5)  
Candidemia (%)
 
5 (3)
 
4 (3)
 

Infection

Fluconazole

Itraconazole
Invasive mold infections (%)*  23 (16)   23 (15)  
    Proven   9 (6)   11 (7)  
    Probable   11 (7)   5 (3)  
    Possible   3 (2)   7 (5)  
Candidemia (%)
 
5 (3)
 
4 (3)
 
*

Proven, probable, or possible infections were defined according to standardized criteria.13  Total percentages were calculated from 148 evaluable patients in the fluconazole arm and 151 patients in the itraconazole arm. One patient in the itraconazole arm developed both candidemia and probable invasive mold infection.

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