Unfavorable prognostic factors for overall survival in 91 AML cases without FLT3/ITD
. | . | Multivariate . | . | |
|---|---|---|---|---|
| Prognostic factors . | Univariate P . | P . | Relative risk (95% CI) . | |
| Age older than 60 y | .0006 | .0011 | 2.607 (1.464-4.644) | |
| Overexpression of FLT3 more than 200 000 copies/μg RNA | .0068 | .0030 | 4.216 (1.631-10.897) | |
| WBC count more than 100 × 109/L | .0074 | .0386 | 2.101 (1.040-4.246) | |
| Cytogenetics | .0801 | — | — | |
| p53 gene mutation | .0805 | — | — | |
| MLL-TD mutation | .1046 | — | — | |
| N-RAS gene mutation | .2350 | — | — | |
| FAB other than M2 | .6483 | — | — | |
| FLT3/D835 mutation | .8687 | — | — | |
. | . | Multivariate . | . | |
|---|---|---|---|---|
| Prognostic factors . | Univariate P . | P . | Relative risk (95% CI) . | |
| Age older than 60 y | .0006 | .0011 | 2.607 (1.464-4.644) | |
| Overexpression of FLT3 more than 200 000 copies/μg RNA | .0068 | .0030 | 4.216 (1.631-10.897) | |
| WBC count more than 100 × 109/L | .0074 | .0386 | 2.101 (1.040-4.246) | |
| Cytogenetics | .0801 | — | — | |
| p53 gene mutation | .0805 | — | — | |
| MLL-TD mutation | .1046 | — | — | |
| N-RAS gene mutation | .2350 | — | — | |
| FAB other than M2 | .6483 | — | — | |
| FLT3/D835 mutation | .8687 | — | — | |
— indicates not done.