Summary of patients' pretreatment characteristics for patients with ITP
. | Patient groups based on the dose of IDEC-131/E6040 . | . | . | . | |||
|---|---|---|---|---|---|---|---|
. | 1 mg/kg . | 2 mg/kg . | 5 mg/kg . | 10 mg/kg . | |||
| No. of patients | 5 | 5 | 5 | 5 | |||
| Men | 0 | 1 | 1 | 3 | |||
| Women | 5 | 4 | 4 | 2 | |||
| Age, y | |||||||
| Median (range) | 55 (48-60) | 56 (29-59) | 55 (22-60) | 58 (51-63) | |||
| Mean | 55.0 | 50.4 | 43.8 | 57.0 | |||
| ITP duration at IDEC-131/E6040 treatment, mo | |||||||
| Median (range) | 89 (20-272) | 50 (7-151) | 82 (17-162) | 53 (9-226) | |||
| Mean | 118.4 | 70.9 | 84.3 | 77.1 | |||
| Baseline platelet count, × 109/L | |||||||
| Median (range) | 18 (9-77) | 31 (14-52) | 20 (9-35) | 35 (24-57) | |||
| Mean | 30 | 30 | 21 | 36 | |||
| Previous therapy, no. of patients (current therapy, no. of patients) | |||||||
| Prednisolone | 5 (3) | 5 (4) | 5 (5) | 5 (5) | |||
| Intravenous immunoglobulin | 3 | 4 | 1 | 3 | |||
| Splenectomy | 2 | 2 | 1 | 2 | |||
| Danazol | 3 | 1 | 2 (1) | 1 (1) | |||
| Azathioprine | 1 | 0 | 0 | 1 | |||
| Dapsone | 1 | 0 | 1 | 0 | |||
| Vincristine | 1 | 0 | 0 | 0 | |||
| Interferon-α | 1 | 0 | 0 | 0 | |||
. | Patient groups based on the dose of IDEC-131/E6040 . | . | . | . | |||
|---|---|---|---|---|---|---|---|
. | 1 mg/kg . | 2 mg/kg . | 5 mg/kg . | 10 mg/kg . | |||
| No. of patients | 5 | 5 | 5 | 5 | |||
| Men | 0 | 1 | 1 | 3 | |||
| Women | 5 | 4 | 4 | 2 | |||
| Age, y | |||||||
| Median (range) | 55 (48-60) | 56 (29-59) | 55 (22-60) | 58 (51-63) | |||
| Mean | 55.0 | 50.4 | 43.8 | 57.0 | |||
| ITP duration at IDEC-131/E6040 treatment, mo | |||||||
| Median (range) | 89 (20-272) | 50 (7-151) | 82 (17-162) | 53 (9-226) | |||
| Mean | 118.4 | 70.9 | 84.3 | 77.1 | |||
| Baseline platelet count, × 109/L | |||||||
| Median (range) | 18 (9-77) | 31 (14-52) | 20 (9-35) | 35 (24-57) | |||
| Mean | 30 | 30 | 21 | 36 | |||
| Previous therapy, no. of patients (current therapy, no. of patients) | |||||||
| Prednisolone | 5 (3) | 5 (4) | 5 (5) | 5 (5) | |||
| Intravenous immunoglobulin | 3 | 4 | 1 | 3 | |||
| Splenectomy | 2 | 2 | 1 | 2 | |||
| Danazol | 3 | 1 | 2 (1) | 1 (1) | |||
| Azathioprine | 1 | 0 | 0 | 1 | |||
| Dapsone | 1 | 0 | 1 | 0 | |||
| Vincristine | 1 | 0 | 0 | 0 | |||
| Interferon-α | 1 | 0 | 0 | 0 | |||