Analysis of the viability of BUBR1–/– mice
. | BUBR1+/+ × BUBR1+/-, no. (%) . | BUBR1+/- × BUBR1+/-, no. (%) . |
|---|---|---|
| Genotype analysis of live births | ||
| BUBR1+/+ | 33 (49) | 92 (36) |
| BUBR1+/- | 34 (51) | 163 (64) |
| Genotype analysis of preimplantation (E3.5) embryos from 5 pregnant females | ||
| BUBR1+/+ | NA | 5 (23) |
| BUBR1+/- | NA | 12 (55) |
| BUBR-/- | NA | 5 (23) |
| Microscopic examination of postimplantation (E6.5) embryos from 7 pregnant females | ||
| Developed normally | NA | 42 (72) |
| Developed abnormally or resorbed | NA | 16 (28) |
. | BUBR1+/+ × BUBR1+/-, no. (%) . | BUBR1+/- × BUBR1+/-, no. (%) . |
|---|---|---|
| Genotype analysis of live births | ||
| BUBR1+/+ | 33 (49) | 92 (36) |
| BUBR1+/- | 34 (51) | 163 (64) |
| Genotype analysis of preimplantation (E3.5) embryos from 5 pregnant females | ||
| BUBR1+/+ | NA | 5 (23) |
| BUBR1+/- | NA | 12 (55) |
| BUBR-/- | NA | 5 (23) |
| Microscopic examination of postimplantation (E6.5) embryos from 7 pregnant females | ||
| Developed normally | NA | 42 (72) |
| Developed abnormally or resorbed | NA | 16 (28) |
NA indicates not applicable.