Table 2. Red cell properties of the... | American Society of Hematology

Table 2.

Red cell properties of the transgenic mice

Short name	β^X,%	α^H%	γ%	MCH, pg per cell	MCV, fL	MCHC, g/dL^*	Reticulocyte %†	Hct	Volume-stimulated K-Cl, FU
Control	—	—	—	14.5 ± 1.0	45.4 ± 0.9	33.0 ± 1.2	2.2 ± 0.5	48.0 ± 1.0	2.0 ± 0.9
HbAKO	β^A, 100	100.0	—	11.8 ± 0.1	38.4 ± 0.7	30.7 ± 0.8	2.1 ± 0.3	48.0 ± 1.0	2.4 ± 1.7
NY1DD	β^S, 75	56.0	—	14.1 ± 0.7	45.5 ± 1.4	35.1 ± 1.3	4.3 ± 0.4	47.0 ± 1.0	3.1 ± 0.3
NY1KO-γL	β^S, > 97	100.0	< 3	14.2 ± 1.1	57.3 ± 1.4	24.0 ± 1.8	63.2 ± 11.8	22.4 ± 1.3	11.4 ± 1.1
NY1KO-γM	β^S, 80	100.0	20	13.1 ± 0.8	53.5 ± 1.9	31.0 ± 1.9	30.1 ± 9.6	34.0 ± 4.6	10.2 ± 0.9
NY1KO-γH	β^S, 60	100.0	40	14.4 ± 0.5	49.3 ± 1.6	31.0 ± 1.9	12.9 ± 2.7	41.0 ± 4.0	8.5 ± 1.4
HbC-L	β^C, 51.3	67.5	—	14.1 ± 0.4	42.7 ± 1.3	35.2 ± 0.3	3.9 ± 0.9	48.0 ± 1.0	6.9 ± 1.5
HbCKO	β^C, 100	100.0	—	13.8 ± 0.9	41.2 ± 3.5	33.5 ± 2.3	12.3 ± 3.8	26.0 ± 8.0	7.8 ± 1.6

Short name	β^X,%	α^H%	γ%	MCH, pg per cell	MCV, fL	MCHC, g/dL^*	Reticulocyte %†	Hct	Volume-stimulated K-Cl, FU
Control	—	—	—	14.5 ± 1.0	45.4 ± 0.9	33.0 ± 1.2	2.2 ± 0.5	48.0 ± 1.0	2.0 ± 0.9
HbAKO	β^A, 100	100.0	—	11.8 ± 0.1	38.4 ± 0.7	30.7 ± 0.8	2.1 ± 0.3	48.0 ± 1.0	2.4 ± 1.7
NY1DD	β^S, 75	56.0	—	14.1 ± 0.7	45.5 ± 1.4	35.1 ± 1.3	4.3 ± 0.4	47.0 ± 1.0	3.1 ± 0.3
NY1KO-γL	β^S, > 97	100.0	< 3	14.2 ± 1.1	57.3 ± 1.4	24.0 ± 1.8	63.2 ± 11.8	22.4 ± 1.3	11.4 ± 1.1
NY1KO-γM	β^S, 80	100.0	20	13.1 ± 0.8	53.5 ± 1.9	31.0 ± 1.9	30.1 ± 9.6	34.0 ± 4.6	10.2 ± 0.9
NY1KO-γH	β^S, 60	100.0	40	14.4 ± 0.5	49.3 ± 1.6	31.0 ± 1.9	12.9 ± 2.7	41.0 ± 4.0	8.5 ± 1.4
HbC-L	β^C, 51.3	67.5	—	14.1 ± 0.4	42.7 ± 1.3	35.2 ± 0.3	3.9 ± 0.9	48.0 ± 1.0	6.9 ± 1.5
HbCKO	β^C, 100	100.0	—	13.8 ± 0.9	41.2 ± 3.5	33.5 ± 2.3	12.3 ± 3.8	26.0 ± 8.0	7.8 ± 1.6

Mean ± standard deviation. — indicates not applicable.

MCH indicates mean corpuscular hemoglobin; MCV, mean corpuscular volume.

Determined by hand-spun hematocrit and Drabkin hemoglobin; the very high reticulocyte counts will result in abnormally low MCHC

Evaluated by Sysmex