Transcript level at baseline and cytogenetic response
. | . | Transcript level . | . | . | ||
|---|---|---|---|---|---|---|
| Cytogenetic response . | No. of cases . | Median . | Mean . | SD . | ||
| Complete, stable | 62 | 0.246 | 0.409 | 0.500 | ||
| Partial to minimal | 67 | 0.253 | 0.362 | 0.330 | ||
| None | 31 | 0.583 | 0.631 | 0.558 | ||
. | . | Transcript level . | . | . | ||
|---|---|---|---|---|---|---|
| Cytogenetic response . | No. of cases . | Median . | Mean . | SD . | ||
| Complete, stable | 62 | 0.246 | 0.409 | 0.500 | ||
| Partial to minimal | 67 | 0.253 | 0.362 | 0.330 | ||
| None | 31 | 0.583 | 0.631 | 0.558 | ||
The transcript level is expressed as the ratio between BCR/ABL and β2M × 100. The level was identical in the patients who achieved a response, either complete and stable or partial to minimal. However, the transcript level was significantly higher in the patients who had no response at all (P ≤ .004, Kruskall-Wallis test). Notice that the transcript level could not be measured in 31 patients, including 14 with a complete and stable cytogenetic response.